NFL Players May Be at Higher Risk of Death from Alzheimer’s and ALS
MINNEAPOLIS – New
research shows that professional football players may be at a higher
risk of death from diseases that damage the cells in the brain, such as
Alzheimer’s disease and ALS (also known as Lou Gehrig’s disease),
compared to the general U.S. population. The study is published in the
September 5, 2012, online issue of Neurology®, the medical journal of the American Academy of Neurology.
The study included 3,439 players with an average age of 57 from the
National Football League with at least five playing seasons from
1959-1988. Researchers reviewed death certificates for causes of death
from Alzheimer’s disease, Parkinson’s disease and ALS. At the time of
the analysis, only 10 percent of the participants had passed away.
The research found that professional football players in this study were
three times more likely to die as a result of diseases that damage
brain cells compared to the general population. A player’s risk of death
from Alzheimer’s disease or ALS was almost four times higher than the
general population. Of the 334 who died, seven had Alzheimer’s disease
and seven had ALS. The risk of dying from Parkinson’s disease was not
significantly different than that of the general population.
To determine if these risks differed by position played, researchers
divided the players into two groups: those who played non-line (“speed”)
positions which included quarterbacks, running backs, halfbacks,
fullbacks, wide receivers, tight ends, defensive backs, safeties and
linebackers, and those who played line (“non-speed”) positions, which
included defensive and offensive linemen. Speed position players were
more than three times more likely to die from a neurodegenerative cause
than non-speed position players. A total of 62 percent of the players
were in speed positions.
“These results are consistent with recent studies that suggest an
increased risk of neurodegenerative disease among football players,”
said study author Everett J. Lehman, MS, with the National Institute for
Occupational Safety and Health in Cincinnati. “Although our study
looked at causes of death from Alzheimer’s disease and ALS as shown on
death certificates, research now suggests that chronic traumatic
encephalopathy (CTE) may have been the true primary or secondary factor
in some of these deaths. A brain autopsy is necessary to diagnose CTE
and distinguish it from Alzheimer's or ALS. While CTE is a separate
diagnosis, the symptoms are often similar to those found in Alzheimer’s,
Parkinson’s and ALS, and can occur as the result of multiple
concussions.”
Lehman said the study was limited by the small number of deaths in the
analysis.
The study was supported by the National Institute for Occupational
Safety and Health.
To learn more about CTE, Alzheimer’s disease, ALS and Parkinson’s
disease, visit http://www.aan.com/patients.
The American Academy of Neurology, an association of
more than 25,000 neurologists and neuroscience professionals, is
dedicated to promoting the highest quality patient-centered neurologic
care. A neurologist is a doctor with specialized training in diagnosing,
treating and managing disorders of the brain and nervous system such as
Alzheimer’s disease, stroke, migraine, multiple sclerosis, brain
injury, Parkinson’s disease and epilepsy.
For more information about the American Academy of Neurology, visit http://www.aan.com or find us on Facebook, Twitter, Google+ and YouTube.
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