Tuesday, 15 August 2017

Repost -Dr. Jeff McCombs- Candida and Cancer expert

Candida and Cancer

Candida and Cancer have been associated through many studies and clinical observations throughout the years. Fungal candida has been identified as the leading cause of deaths due to sepsis in hospital settings, but can occur in anyone. Severe suppression of the immune system leads to an increased risk of death, while less severe cases can lead to diabetes, asthma, allergies, and over 100 symptoms and conditions. Candidemia, candida in the blood, remains a major cause of morbidity and mortality in the health care setting.
In the oral cavity, candidiasis is the most frequent opportunistic fungal infection and is associated with pre-cancer and cancers. For those people who do have cancer, radiation and chemotherapy are the two main options for treatment put forth by the medical field. Researchers at the Regional Cancer Institute “revealed the presence of C. albicans fungi as most significant oral cavity pathogens in radiotherapy and radio chemotherapy cases.” Here we see that candida can cause cancer and medical treatments for cancer can cause candida, seeming to create a vicious cycle.
One of the means by which candida promotes cancers is through inflammation. Inflammation is one of the common links to all cancers and candida has been shown to promote inflammation in the body, and inflammation further promotes candida. One of the pathways that has been recently discovered by cancer researchers is via the release of pro-inflammatory IL-15 in response to chronic infections such as candida.
Another pathway is through blood sugar imbalances. Candida can cause blood sugar imbalances and these imbalances, high and low, are associated with causing immune system suppression. Immune system suppression is a part of all cancers. The vast majority of IFIs (Invasive Fungal Infections) in the ICU are due to Candida spp. The incidence of invasive candidiasis (IC) has increased over recent decades, especially in the ICU. Surgeries can cause immunosuppression and are typically associated with a higher incidence of candida infections. Most cancer patients lack the appropriate immune responses and candida increases immune system dysfunction.
Candida has been shown to be involved in lung cancer, which is one of the most common cancers worldwide and a leading cause of death. Lung cancer is the most common cancer worldwide, with “1.35 million incident cases annually, and consists one of the leading causes of mortality worldwide.”
One medical doctor, Dr. Simoncini, believes that cancer is caused by the fungal form of candida. This of course leaves out many other possible known causes such as chemicals and heavy metals, but it does align itself to a growing body of research on candida and cancers.
It’s important to note that both antibiotics and candida are associated with causing cancers, and antibiotic use is the major cause of fungal candida. Given this link, it is likely that candida plays a causative and supportive role in creating cancers. The more antibiotic exposure one has, the greater the likelihood of contracting cancer.
Reversing the effects of antibiotics, boosting immune system responses, and restoring balance to the flora of the body should be a part of everyone’s approach to addressing imbalances that can lead to cancer.
Take back your health.   Live the life you create.   Dr. McCombs Candida Plan.
Dr. Jeffrey S. McCombs, DC, is founder of the McCombs Center for Health, the Candida Plan, the Candida Library, and author of Lifeforce and The Everything Candida Diet Book.
https://twitter.com/DrMcCombs
https://www.facebook.com/groups/candidaplan/
 Candida and Cancer

Dr. Jeffrey S. McCombs, DC, is a third generation graduate of Palmer College of Chiropractic (1984). He is licensed in the states of California, Illinois, and Arizona. He is a member of the California and Illinois Chiropractic Associations, the International Association for Specialized Kinesiologists, and the American Holistic Health Association. Dr. McCombs developed his Candida Plan which is a detoxification and dietary plan that counters the detrimental effects of antibiotics and reestablishes the normal body flora, detoxification pathways, and regeneration cycles of a vital,

Monday, 14 August 2017

Cancer Research and Ms Society






                         Are frauds and only raise millions to sustain their own existence, shame on them.
                                                and we suffer because at their hands
                                                  and believe their fictitious

                                   FALSE     HOPE

 

                  Ireland, Wales, Scotland and England need to wake up        

Saturday, 12 August 2017

Galantamine and CFS

Effects of Galantamine Hydrobromide Treatment on Dehydroepiandrosterone Sulfate and Cortisol Levels in Patients with Chronic Fatigue Syndrome.

Turan T, Izgi HB, Ozsoy S, Tanrıverdi F, Basturk M, Asdemir A, Beşirli A, Esel E, Sofuoglu S. Department of Psychiatry, Erciyes University Medical School, Kayseri, Turkey.


OBJECTIVE: Mental fatigue, cognitive disorders, and sleep disturbances seen in chronic fatigue syndrome (CFS) may be attributed to cholinergic deficit. A functional deficiency of cholinergic neurotransmission may cause the hypothalamic-pituitary-adrenal axis hypoactivity seen in CFS. Therefore, we investigated the alterations in stress hormones such as cortisol and dehydroepiandrosterone sulfate (DHEAS) in CFS patients before and after 4-week administration of galantamine hydrobromide, a selective acetylcholinesterase inhibitor, and aimed to investigate whether there are any relationships between the probable hormonal changes and cholinergic treatment.

METHODS: Basal levels of cortisol and DHEAS were measured in 29 untreated CFS patients who were diagnosed according to Centers for Disease Control (CDC) criteria and in 20 healthy controls. In the patient group, four weeks after 8 mg/d galantamine hydrobromide treatment, cortisol and DHEAS levels were measured again. After the treatment 22 patients who stayed in study were divided into two subgroups as responders and nonresponders according to the reduction in their Newcastle Research Group ME/CFS Score Card (NRG) scores.

RESULTS: Important findings of this study are lower pre-and post-treatment cortisol levels and in all CFS patients compared to controls (F=4.129, p=0.049; F=4.803, p=0.035, respectively); higher basal DHEAS values and higher DHEAS/cortisol molar ratios which were normalized following four weeks' treatment with 8 mg/d galantamine hydrobromide in the treatment-respondent group (F=5.382, p=0.029; F=5.722, p=0.025, respectively).

CONCLUSION: The findings of the decrease in basal DHEAS levels and DHEAS/cortisol molar ratios normalizing with galantamine treatment may give some support to the cholinergic deficit hypothesis in CFS.

PMID: 20046396 [PubMed - as supplied by publisher]





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Thursday, 10 August 2017

able 4.1



Residual insecticides for use against bedbugs


Insecticide Concentration in spray (%)



malathion 2.0

fenitrothion 0.5–1.0

propoxur 2.0

carbaryl 1.0

diazinon 0.5

bendiocarb 0.2–0.3

fenchlorvos 1.0

pirimiphos methyl 1.0

propetamphos



Monday, 7 August 2017

http://candida-yeast-infection-relief.com/testimonials.shtml

Testimonials


"I have been using your CandXpel and Total Flora 15 for two months and it has really helped me to control my appetite and diminish my outbreak of yeast infection. I have been eating healthy and watching my sugar and bread intake. Thank you"
Gayla C 5/6/16
Dear Robert,
"I am pleased with your product. I am almost done with my Candxpel and I feel the difference already. My energy is soaring and I feel better each day. I will continue for three months. I still get chemo shots but tolerable!
Thank you"
Angie C 4/25/16


"Even though I had never heard of Candida until I was in my late thirties (now 58), it is clear to me I have been struggling to balance it most of my life. As a teenager I had been on antibiotics for acne for several years, topically and orally, resulting in chronic diarrhea which morphed into chronic constipation, compromising my health in a multitude of ways. Even though I ate mostly organic, healthy foods most of my life, I was never able to resolve many chronic issues. I was treated by some of the top Candida specialists, but most of the treatment was so harsh on my liver it was never resolved and eventually led to colon cancer.
I started the CandXpel just about 6 weeks ago and am feeling really well with it. The first 2 weeks were a bit rough, but nothing compared to what I experienced with strong herbal antifungals. At around the 2 week mark I had large bumps appear (itchy and burning), mostly around my left ankle, but some random ones. I thought I might have bed bugs, but realized I was also having a large amount of itchy discharge from all orifices. I realized it was the CandXpel at work. In a few days it passed, and I have felt increasingly better since. I am sensing this elixir really goes deep and drives out the burrowing pests at their roots. I am excited to find something so effective and gentle that I have no issue staying on it 6 months or a year if that is what it takes. Thanks for creating such a gentle and effective aid to restoring health!"
Terry G 4/8/16
"It is with good health and gratitude that I am writing this testimonial for Pineal Gland Elixir. Prior to taking the Pineal Gland Elixir, I was catching every runny nose, sore throat, cough, virus and flu that my young granddaughters had come down with. Unfortunately, the illness would become much more serious for me than for the 2 and 4 year old little girls. Twice I suffered from deep lung infections accompanied by fevers of 103 or 104. When I asked Robert Harrison, Natural Health Consultant of Get Healthy Again, what I could do to boost my immune system, he identified that my pineal gland was very low and recommended I take this elixir. Within a very short time, I began sleeping more soundly and deeply than I had for many years and I felt much more rested when I awoke in the morning. I regained my energy and strength which allowed me to live the active and engaged life that I am accustomed to living. Now after six months of taking the elixir and being exposed to numerous colds, coughs and fevers, I continue to enjoy a good night's sleep, excellent health and abundant energy.
In addition to Pineal Gland Elixir, two months ago I began taking Optimal C, CandXpel and Stress Reducer Elixirs. I am frequently told by friends and family that I look very healthy, relaxed and happy. Based on the life-enhancing benefits I am experiencing, including feelings of deep peace, contentment and increased self awareness, and the positive feedback I am receiving, I highly recommend and give all three elixirs the highest ratings.
To Robert, who helped save my life when I was gravely ill from a serious case of Candida, I offer a deep bow of gratitude for sharing his unsurpassed skills and knowledge, his kindness and compassion and his sincere commitment to helping people become healthy. "
Rosalyn M.

 

 

Candida Diet Didn’t Work For Him, But This Did:

Written by a Happy Customer
Charlie had his first bout with Candida back in 1982, and since then has been struggling trying to get rid of it. A strong believer in nutrition and natural medications, Charlie tried modifying his diet, which seemed to work temporarily, but it always seemed to re-occur. Doctors didn’t even know what the real problem was. Dubious, Charlie tried CandElim. Read below or listen to Charlie’s fascinating story to discover how Charlie now lives Candida-free.

Click to play a HIGHLIGHT of this Candida relief story.

Full Testimonial

Transcript

Dr. Sharon Livingston: So I am Sharon Livingston and I am talking to Charlie. So we are talking today about your experience with Robert Harrison’s products and specifically can you tell me a little bit about you know what brought you there, how you got there, what you tried, what happened, just kind of tell me the story?
Charlie: Well ok, I found him through the internet and I read his treaties on what he has been doing. I have been dealing with Candida for about 30 years, 28 somewhere 26, 28, 30 years.
Dr. Sharon Livingston: How did you know you had it?
Charlie: Well you know I was always interested in self medicating through diet and I just knew that so much would happen to your body through what you ate and I did some research and I worked for a health food store in Bethel, Connecticut and I did, I think it is called Nystatin and it really, it really helped so I knew I had faith that there was such a thing as Candida number 1. What brought it on was a throat condition that I had.
Dr. Sharon Livingston: What was it?
Charlie: I beg your pardon?
Dr. Sharon Livingston: What was the throat condition?
Charlie: Well it was a, no doctor could tell me what it was, that was the problem. It was like a dry feeling in my throat and it would move around and this was over the space of weeks, months, years and I have found out that sugar, when I eliminated sugar from my diet it almost, it really helped what I was doing. So that got me started with Candida and I did some research and doing the Nystatin and the no sugar I eliminated my throat problem. However, I have had my problem, was brought on by antibiotics I believe. Many, many bouts with antibiotics. They have saved my life plenty of time, but what happens is that I go through this food sensitivities and it manifests mostly in my throat. I am sure other parts of my body, too, but that is where it was mostly felt and it did come on through working. I am a carpenter and it did come on in conjunction with sanding a particular type of wood, bass wood, it smells like pepper and that is when it came on and that was about 30 years ago. It must have been 1982, yeah, it was 1982. I think so because that is when I bought my property here and that is when I was working in Manhattan on this sound stage. Not a sound stage, we were building a recording studio and it was hand Helmholtz resonator that we were making and we were making it out of bass wood for some reason, a semi hardwood. At any rate I subsequently have had reoccurrences with Candida and a lot of times I would, just because it comes on so suddenly, I wouldn’t do the Nystatin and the, I would just eliminate sugar and I would hope for the best, and finally I wanted to do something about it because it was so pervasive. What was happening with my throat and the doctors said there is nothing there, the doctors couldn’t, you know, it wasn’t, I had what is that called when you take iodine for, thyroid. I had my thyroid checked because I had symptoms of that happening, heart palpitations etc. It all turned out to be just Candida and the reason I know it is because I took, I got the Candelim and I was very skeptical almost doing tasteless water and the directions were a little bit ambiguous at first. I think he ended up changing them to do it with meals. There were two different directives on the label, and two subsequent bottles that I got, straightened that out and then went off of it for a month and it all started to come back, started again and then it went away and I had something happened that was not accounted for that I attribute to Candelim and I had a fungus, a type of fungus that would appear on the tops of my feet. Went to the doctor he gave me this super salve that you put on, Corticortisone 10%, not that stuff you get over the counter.
And it would control it. It would start with a miniscule red dot and it would expand twice, it would go twice the size each day, it would be twice as big, so you could imagine once it gets to be a quarter inch and then the next day it’s a half inch its very scary. At any rate it was under control and I would chase it all over my feet, it totally disappeared and I have been doing this for 10 years, it totally disappeared.
Dr. Sharon Livingston: Wow.
Charlie: It totally disappeared if this has to do with, now is Candida is that, that is a fungus isn’t it?
Dr. Sharon Livingston: Yep.
Charlie: Yeah so I attributed it to, I guess I just have been chasing it, it did disappear once before but that may have been in conjunction with something else but it came back and it was on both feet I think once and I think it started with a mosquito bite.
Dr. Sharon Livingston: Oh my gosh.
Charlie: And there is a fungus, it’s a killer fungus that starts with a mosquito bite.
Dr. Sharon Livingston: Oh my goodness.
Charlie: Yes, if you look it up on the Internet you will find it, but there is a fungus that you get from scratching a mosquito, I don’t know if it was a dead mosquito or whatever, but it is devastating. I don’t know whether this is that, but untreated its just incredibly viral. So any rate that is my story. I really feel that I am going to get it for my son for his birthday because he has a skin rash on his face that the doctors attribute to some sort of fungus and I am going to start him on Candelim and he is already interested in Candida too he is very aware of what he eats, he is a chef.
Does this sound plausible or I imagining, I am not, I know it is psycho-semantic illnesses are but I just feel that this really works, as I say I was skeptical, but it really works and I just wanted to commend the good doctor for doing this. It’s just really amazing. Where the heck did he come up with oils of conifers? Apparently the oils that are in it is mostly conifers except for the few which is, I don’t know, it might be a conifer.
Dr. Sharon Livingston: Well this is not my area of expertise, my area of expertise is in interviewing people to find out what happened and although I definitely have an interest in all kinds of health related things, so I have done a lot of research on health myself, but it sounds fantastic. What were you looking for when you were searching on the internet what were you actually searching and what was it that Robert said in his…?
Charlie: Well first of all Candida elimination that is what I looked up and the name of his product is Candelim.
Dr. Sharon Livingston: Right.
Charlie: So it really came up first you know first or second or third you know between 1, 2 or 3. I think it came up number 1 when I looked up Candida elimination.
Dr. Sharon Livingston: Wow.
Charlie: It came up and I read what the research that he had been doing and how much involved he has been in it. I didn’t realize that he was involved with so many other health claims, but this one seems to have done it, it’s a 95% better and what happens is that I do go off my sugar free diet I mean just totally sugar free, no sugar in anything, I read labels, but you know I slowly go off of that as I get better which you know I have more control over it now so its nice to be able to have something with yeast in it for instance I couldn’t eat bread or drink beer for 28 years.
Dr. Sharon Livingston: Wow. Otherwise you would get this thing in our throat.
Charlie: Well the thing in the throat and I would also get essentially bleeding hemorrhoids from beer.
Dr. Sharon Livingston: Wow.
Charlie: Oh yeah, other people this isn’t unique to me, it has happened with other people, too, but you know perhaps it is one that keeps healing and keeps breaking, I don’t know exactly the physiology of it but no more, it was like I was in beer jail for 28 years and now I drink non alcoholic beer, I am addicted to it.
Dr. Sharon Livingston: That is really cute.
Charlie: It is really good for you too, beer is really good for you and you know I am not saying that the addition of all of those B vitamins hasn’t done anything to my homeostasis, but it may have because beer really is good for you. In most I think cultures started by drinking beer, that was their main stand 10,000 year old cultures, beer, good stuff.
Dr. Sharon Livingston: That’s great.
Charlie: Yeah but at any rate that is my story, I just really feel that it has helped.
Dr. Sharon Livingston: And may we use your story on his site?
Charlie: Yeah sure. Now I on my foot thing when I stopped it one of the feet came back, on one of the feet and then I started it again, when I started it again about oh, three weeks ago, four weeks, just about three weeks ago, it went away again.
Dr. Sharon Livingston: That is really cute. Well Charlie thank you very very much and I think that it is funny we both migrated from New York to New England.

Candida, Headaches and Fatigue Now Gone:

Written by a Happy Customer
Gina suffered from Candida almost all of her adult life. Birth control pills and hormone treatments made her Candida worse. She had trouble sleeping, felt irritable most of the time, and suffered flu-like symptoms, too. Finally tired of being sick, she set out on a quest to cure herself. Like most people, Gina was cynical when she came across CandElim, and was even concerned about the cost. But she finally overcame her own doubts and gave it a try. Find out why Gina now says that CandElim is “it’s the strongest, the best stuff I have found so far ” to eliminate Candida.
Click to play a HIGHLIGHT of this Candida relief story

Click play on the player below to listen to the FULL testimonial now.

Disclaimer: This person’s experience is not indicative of what you will experience.

Full Testimonial Transcript

Dr. Sharon Livingston: Hi Gina, it is Sharon Livingston. How are you today?
Gina: Oh I am pretty good. How are you?
Dr. Sharon Livingston: So we are going to be talking about your experience with the Candida products and I would love to hear your story, like how did you come to Robert Harrison’s website and give me a little background and then tell me what happened?
Gina: Well I have been fighting Candida really all of my life, but two sections of it when I was in my 20s I took birth control pills and that is when it got worse, and then in my middle 40s I started taking some bioidenticals hormones and it got really bad after that.
So I was on a quest, I was really sick with it and of course there are not that many doctors out there that know about it and can help you.
Dr. Sharon Livingston: When you say you were really sick – what kind of symptoms?
Gina: I was, it was attacking my nervous system and my blood pressure was going up, I was having headaches, tired, my ears, itching, I had really bad eczema, I was having trouble sleeping, very irritable, sound like you have the flu all the time. It’s a weird feeling, and I couldn’t eat anything. If I ate any sugar or carbs or anything my symptoms would just flare up and its just a terrible thing and I would not wish it on anybody because fungus is so hard to get it to die, especially when it gets to a stronger state and it mutates and it is just really hard.
So I have surfed the internet a lot looking for answers, buying books and trying to scope it out myself and I didn’t find him for awhile. I only found Get Healthy Again. When I punched in I think it was systematic Candida I had to clue in the computer I couldn’t just say Candida I had to say like it was systematic, like it was in my blood and then Get Healthy came up again. So then he had this whole analogy like this huge sheet on explaining it and why I wasn’t getting rid of it even though I was taking probiotics and antifungals and you know he was saying that you have to kill the spores and how it mutates and he explained like this really good analogy.
So right away I didn’t buy his products because they were expensive so I was kind of fooling around with a few other things and nothing was working and I was still, I felt just terrible and I thought I got to do something about this I can’t take it anymore. So then I bite the bullet and I bought Candida Clear first because it was like a detox with it, so I thought, “OK, I want to detox too.” So I was really sick when I first started taking that product. I was having such die off and I would e-mail him because I didn’t know what was going on and he would always answer my questions and tell me to cut the dose back, ease into it slow, he was very helpful through the process.
So then I did as he said and I started feeling better on it but I didn’t feel 100%, you know I couldn’t quite get it, if I started eating sugar you really have to, when you take these parts you really got to cut the diet, cut everything. I tried like every now and then put back my bioidentical hormones and I couldn’t it would just flare back up again so it was still in my system and he said that that would get it under control but it would take like six months. So I still have that product but the next time I thought that I would try it, he told me to try the Cand Elim, he said try that, so I ordered that.
Dr. Sharon Livingston: The Candelim?
Gina: So I know that it is working and that if I stop taking it, it starts coming back so it’s the strongest, the best stuff I have found so far and I am hoping that if I stay on it long enough and really watch the sugar and the hormones I don’t go back on those. That is obviously what is feeding it, too. Then I will be able to get my body back in balance and then I am also going to try the probiotics because I do take another probiotic care but I am going to try his to see if his is any better. The problem is the fungus will mutate. It gets used to stuff, but his products, the way they kill it it doesn’t mutate as much. So that is another thing its like I don’t have to rotate, like before I was rotating this fungals like every five days because it would stop working.
Dr. Sharon Livingston: So having had this experience, have you talked about it to anybody else, have you recommended it to anybody else?
Gina: Yes I have.
Dr. Sharon Livingston: What did you tell them?
Gina: I just, well they come to me because they know I have been through it and done it like people that are struggling with it and I tell them, I tell them about his website and then I say this is the best stuff that I have found. But it’s expensive. A lot of people don’t want to try because of the money, and then they think well that is not going to work they get rather discouraged, or they feel like that is just a hokes you know its hard to, but once you have had it and you felt so sick you cant, you know you can’t live like this, you get so, you have to get to your desperation point where you are ready to just spend the money and then try something and see if it works.
Dr. Sharon Livingston: I am so delighted that you had a good experience and what about Robert himself, what did you think of him?
Gina: I really liked the fact that I could e-mail him and he responded right back to me and he always told me what was going on, like he knew his products, he knew how to explain it to me so I understood and he was just talking like he is very very familiar with it.
Dr. Sharon Livingston: So I want to say thank you so much, this is exactly what I was hoping how the talk would go so you know we would understand the problem and what you tried and what has been the results so far. So is it ok if we use this audio on his site or in his mailings?
Gina: Yeah.
Dr. Sharon Livingston: That would be awesome.
Gina: Yes go ahead. Whatever can help more people.
Dr. Sharon Livingston: Well have a wonderful Mother’s Day.
Dr. Sharon Livingston: And thank you so much for our talk.

Candida and Extreme Pain Eliminated:

Written by a Happy Customer
Do parasites cause Candida? Are food allergies related to Candida? Are flu-like symptoms one of the ways that Candida affects you? These were all questions that Peggy had. After returning from a vacation with a persistent illness, swollen fingers and hands, and a pain so bad she says “her skin hurt all over”, she ended up in the hospital. Skip ahead to the present day, and Peggy’s discovery of Robert Harrison and his Candida website. For the first time, she really learned about how Candida affects the body, and how to fight it. She knew she finally found a reliable resource she could trust. After 12 years of constant pain, 24 hours a day, 7 days a week, she is finally pain free. Find out what that’s like by listening to this compelling audio.
Click to play a HIGHLIGHT of this Candida relief story.

Click play on the player below to listen to the FULL testimonial now.

Disclaimer: This person’s experience is not indicative of what you will experience.

Full Testimonial Transcript

Peggy: My story is a long one, Sharon, but I will tell you. Initially this is why I was so interested in the Candida products because it seemed to me I never heard anything like this before.
Apparently thousands of people a year travel and get infected with parasites and nobody talks about it because nobody can seem to get help. They just get sick and nobody can ever find where so they can’t prove anything.
I was literally sick on the way home on the plane. I had eaten. My mother and I had eaten the same thing, dinner. Two days later, throughout the two days, I was just not feeling myself. Not like violently ill or anything, but I got this rash and then the next day I had fevers, the next day I almost couldn’t get out of bed just for the feeling of being hit with the flu. For two more days I am literally in bed, like chronic fatigue syndrome. My joints hurt, I am swollen, my fingers were unrecognizably swollen. My face had swollen so that it looked like I was allergic to bee stings and stung everywhere. You know that kind of swollen?
Dr. Sharon Livingston: My goodness.
Peggy: So I go to a doctor and they say well you are allergic to something you ate or whatever and they try a couple of medications. Two weeks later I am sound asleep in bed, nothing. You know I had been trying to get up and go to work and I am calling in sick. Two weeks more pass still in the same condition. I had all the same symptoms but everything got worse: the swollen, the joints, the pain, the fevers, the chills and meanwhile not knowing exactly what is happening. To a lighter extent my mother is having the same symptoms and we were the only two who ate the night before.
So you know basically after that initial infection which was like a month long it seemed like I couldn’t get out of bed, I finally got up and went back to work and did some things and I had been tired. That rash went away and the swelling went down but I still had some joint pains. But as this year goes on now after this I continue to lose weight and I started at 98 pounds.
Dr. Sharon Livingston: Oh my.
Peggy: And I was 5’4”.
Dr. Sharon Livingston: Oh my.
Peggy: These are really serious bugs when I tell you I had to be treated with a medication that we had to go get weekly in New York City that cost thousands of dollars a week.
Dr. Sharon Livingston: Oh my god.
Peggy: We are not talking a little tired like I put on my pajamas and went to bed and just called in sick to work. I am telling you I could have slept through my house being on fire. I used to be a light sleeper, barely sleeping 5-6 hours a night and feeling fine in my 30s.
So we would go straight back then by the end of that five months of testing to me having that same rash with the same swollen joints and the same swollen face and now I am thinking to myself “holy shit what is wrong that I could be so seriously ill?” Literally if you touched, or if I had to turn over in the bed my skin would hurt, my head hurt so bad, my hair hurt. I can’t explain to you the pain I was in and it was just over joint pain. So I didn’t know what to do. I traveled around, researching as much as I can and I get myself to a rheumatologist who starts testing me for every possible auto immune disease there is. As far as the tests that can be positive tested, positive for lupus. But it took three more years to figure it out. That three years I was so sick because it was just continuing to ravage. One day I tried to get out of bed I basically fell on the floor and my husband said, “all right I will help you up.” I went to go grab him and I couldn’t move. I was paralyzed from the nipple line down. I felt nothing.
Dr. Sharon Livingston: Oh my god.
Peggy: So he gets me to a hospital in New York City because of that specialist who gave me the name of the biggest lupus person there is. He sees me in Columbia Presbyterian and he says, “look we are going to give you these huge doses of steroids now because we are going to try to save your spine. Apparently there is an inflammatory process that has totally eaten through your spinal track.
“So you know we don’t know if you are ever going to be able to walk again, this is a syndrome called Transverse Myelitis and its like the million-to-one complication of lupus because you were never actually treated early or quick enough.” They couldn’t get control of it so it just continued to eat through the bone in my spine to the point of cutting off the nerves. So this guy got thousands of milligrams of steroids into me fast enough, but he told me that he is in his mid ‘60s (at that time 12 years ago) and that he was the number one physician in those Consumer Reports for rheumatology, the number one guy, I mean $5,000 to walk in type of situation. If I didn’t know somebody I never would have gotten in to see him. That is just how it is, but he has seen three people in his entire career who have this complication of lupus and none of them can walk. I was the fourth person and I got the steroids in fast enough and I was able to walk again, albeit barely. This is where I started off with lupus, so now none of my medications could get control of lupus.
Dr. Sharon Livingston: What a horror.
Peggy: I ended up with two years of chemotherapy to try and contain this lupus and not have it ruin the rest of my body. During that time I was so weakened that now it affected my second organ. The first was the bone, now it affected my lungs, and I was so tired and asleep for 20 hours [a day], for three years of not waking up, that my oxygen levels were so low that when I got to the emergency room I was directly put on a respirator. I couldn’t even tell them who I was. They didn’t even know if I was going to live through it. Apparently they told my husband between the bone situation and having such a low oxygen level we don’t even know if she will wake up and know who she is. We don’t know how long she has been without oxygen. I don’t know how I hibernated throughout that and lived with enough oxygen to not have my brain totally affected. It’s a lupus pneumonitis so it has all the symptoms of pneumonia but it’s not actually bacteria like you would have in a normal situation. It’s just an inflammatory process that has all the same symptoms. In other words, they treat this pneumonia, and since there is no bacteria. It’s just the lupus is fooling the body into symptoms of pneumonia, there is nothing really to treat. You have to either see if that person is strong enough to get over it with anti-inflammatory drugs. So eventually I wake up but of course you could imagine how I come home from this hospital. I was so bloated from these steroids between the bones and the pneumonia. I was like 140 pounds, the size of my abdomen.
So this pump in my abdomen: I have only had it for a year-and-a-half. That is how much time I was in bed not taking care of my family, and basically on pain medication to just get to the bathroom. Now I had a year-and-a-half, my youngest was a year-and-a-half old. She doesn’t remember me well so now that I am up and back on my feet with this pump she is thrilled. My older two feel like I was taken away for good because I never got up again.
I couldn’t even get to a food store so I used to have food delivered, and then my husband would pick up fresh items to get us through.
It was literally a homeopath that I found in Hudson County that I used to go visit. Her initial test, I am sorry, but her initial testing was through looking at my tongue and all symptomology and she was to give remedies that she would make and I would bring home and it was the first time anything felt better and you could actually see an improvement, but because I was so sick I would have had to have worked with her on a continuous basis probably for five years because of, you know, how these remedies work. I just keep getting sick whether I was having the chemotherapy like I was trying medically and doing that at the same time not realizing that you have to just get sick enough not to take the medication and go ahead medically to be able to let the homeopathic medication to work.
So literally when I got on Robert’s website not only is the information written clear enough for I believe some lay people to understand, it is still over a lot of heads. I gave it to my mom to see the website and see what was making me feel better so you know I gave it to her, and she had a hard time understanding and she is a very smart person.
Dr. Sharon Livingston: What was it that it said that it excited you?
Peggy: It was the way he explained everything so that you would understand how you got sick. Never once did he say, “take my product and you will get better or you will you now feel this.” He wasn’t selling his product. He was interested. The information was set out for you to understand why you lost function because of this digestive process and it made so much sense according to the symptoms and things matched up. You know how many doctors have I seen throughout this 12 years that couldn’t put two and two together for it to make sense enough for me to follow through with them? I would go look for another physician and this one person, whoever wrote these articles on that website, literally just wanted you to understand it so that you could make a decision and he would say, “look even if you took this information and went elsewhere this is how it is affecting you.”
Dr. Sharon Livingston: What specifically did he say?
Peggy: I can’t explain it to you; he just wasn’t trying to sell you anything.
There are so many people out there that every time you get onto a site they will say “well I promise that you will do this if you buy this” and he didn’t say that. His articles were for you to understand how you got sick and what it is doing to you even if you left that website and went somewhere else and never took his products. You could tell by the way it was written, and like I said I am a medical person, that he wasn’t interested that you took his products. He was interested that you understood the process.
The process of how yeast, how antibiotics affect your digestive system and what happens when yeast takes over, and all the drugs that I took, that is exactly what happened. The steroids drop your immune system function enough that the regular good bacteria go away and you start to develop symptoms of Candida or yeast infection, medically not gynecological. Orally, in your fingers, under your nails; the signs that you would have more of a yeast infection as far as how you felt, and I am talking about in your gut, in your colon, and after all of the antibiotics and steroids, that is exactly how I felt. So if I couldn’t even get up because I couldn’t digest food and I had an overgrowth of bacteria in my colon that would continue to make me tired and not let me digest food and not let me heal, how could anything I ever did for myself with the lupus or anything else work?
I sent him a note because it said, “Contact us with any questions or concerns,” so I wrote this note to lightly explain what happened. I told him about my diagnosis and say these are the products that I thought would help my situation if you have any insight or time to help me I would appreciate it. I have taken some of these products before through a homeopath so I have some idea of what it could do for me if I could get going with some advice, because I am disabled and stuck at home and this physician is no longer in my area. Well in two days this man answered my mail and said this is what could help this, this is what could help this, and this is what could help this. You don’t have to take my products but this is what they are, if you choose to use them this is what should happen, this is how you should take it, this is what, whether I used his products or someone else’s, and when I said to him, “My god you know to be honest I wrote back this is a lot, some of the products are hundreds of dollars for just a month,” I said what are the top three because I cannot afford to do this at the time. I have been disabled for 10 years not working. My husband is a police officer, just at the time that I was taking care of myself with the lupus you know with my family right before this pump was put into my abdomen, the medication that it took for me to be able to get up and go to the bathroom and stay well and not have an infection was $15,000 a month. We had to put out in cash on a credit card and wait to be reimbursed by an insurance company.
So some of the products are literally $180 for one bottle and I would need three of them a month, but he said to me $35 each supplement no matter what it cost. Now can you tell me would you believe this person wanted to help you or not?
So how could I not literally take his advice and do what I could and at that point? At the $35 I ordered the first four products out of the 10 he told me, and I got started. In that first two months not only was my memory better but my fatigue was improving. There are times where if the lupus is active I can still sleep 20 hours a day, that has never changed in 12 years, but it hasn’t happened since I have been taking the products.
And I am taking candelim powder and the candelim elixir and those are the two for the yeast, the digestive track. I am taking nymsar and quzu.
Dr. Sharon Livingston: What are those for?
Peggy: They are both for inflammatory conditions so they would help direct my immune system to function the right way after it decreases the inflammation. And I am taking mind matters for the cognition system, the memory problems which are improving daily after that initial month and msm powder and, I don’t know how to say that one, but that is for the pain, they are both for the pain and the new one’s penuvu for pain. The pain has improved so I am standing upright. I have not been standing upright for seven years.
Dr. Sharon Livingston: Wow.
Peggy: All of these put together are having my immune system function instead of at a super high level attacking everything that comes near my body to not reacting so quickly and it’s cleaning up my body so the stuff that is working against the yeast is clearing out the bad bacteria and allowing the good bacteria back in my digestive system so that everything comes back into proper balance.
Honestly with everything working exactly as he told me it would in his initial letter to me and I tell you you could tell he was busy because he would write the name of the medication, what it would do like a dash and what it would do and how to take it. I no longer have pain 24 hours a day, seven days a week. I have had 12 years of solid pain there isn’t a day that I haven’t had so much pain I have taken 10 or 12 morphine doses a day. I don’t even take the pills anymore.
Listen let me just ask you, what are you hired by him to do this for him is that what this is?
Dr. Sharon Livingston: Yes.
Peggy: Ok I get it, all right.
Dr. Sharon Livingston: But you know I don’t work for just anybody. I am a psychologist and I have a lot of interests in alternative health and you know I have my own training so I only take people that I feel like I want to sing their praises.
Peggy: Oh my goodness please I can not tell you what he has done for me, I can not tell you. I don’t even know him and I feel like I would be able to recognize him in a crowd by how he would look.
Dr. Sharon Livingston: Oh that is great.
Peggy: I only say that because I call him my Alaskan Angel.
Because I don’t know how I would have ever felt this way without him and I only say that because I have felt so like I was being chased by a bat every time I would get one step ahead it would be two steps back because something else would happen. But this is the first time honestly that I have caught a break in the 12 years.
Dr. Sharon Livingston: Peggy you are fabulous, thank you so much and I wish you continued improvement and a wonderful birthday celebration today with your family.
Peggy: And you for your family and much success for both you and Robert really, honestly.

Candida and Antibiotics Link Finally Broken #2:

Written by a Happy Customer
Roslyn almost died from liver failure on June 1, 2009. After being in the hospital with an IV of antibiotics, her digestive system was almost destroyed. After leaving the hospital, she never felt right again. And no matter what she did, she just felt worse. After doing some reading — and discovering that she had a vaginal yeast infection — Roslyn first read the words “Candida” and finally realized what she was suffering from. Find out how her digestion kept getting worse, how she lost weight almost uncontrollably, and how her health continued to decline. But then, after discovering Robert Harrison and his supplements, her life finally turned around. Find out how in this compelling audio.
Click to play a HIGHLIGHT of this Candida relief story.

Click play on the player below to listen to the FULL testimonial now.

Disclaimer: This person’s experience is not indicative of what you will experience.

Full Testimonial Transcript

Dr. Sharon Livingston: Hi Roselyn, this is Sharon Livingston. How are you today?
Roselyn: Oh good. How are you? Oh that’s right an interview.
Dr. Sharon Livingston: So, well I am just kind of curious how you came to the website, you know what brought you there to begin with and what your experience has been. I would love to hear about it.
Roselyn: Ok, I self diagnosed Candida after I had a serious illness, a sudden serious illness almost three years ago. June 1st will be three years, and my husband rushed me to the emergency room. I almost died actually.
Dr. Sharon Livingston: Oh my goodness.
Roselyn: I was very close to liver failure. So fortunately, we got there in the nick of time and I was in the hospital for about four days and then I was able to go home. But I had been on IV antibiotics for 48 hours, a very intensive cocktail of IV antibiotics for those four days, and I don’t do very well with allopathic medicine. Anyway, so this was really bad because at some point I was begging them to take me off because I felt so sick from the antibiotics, but they said they had to keep me on them until the culture, the bacterial culture, came back. So that came back negative and they were finally able to take me off of them.
So I came home and my whole digestive system was just, how do I explain this to you, I couldn’t take in any food, I felt sick to my stomach. It is like I started to feel better from what they could only diagnose is sepsis caused by a virus. So I started to feel better but then the intensity and the quantity of antibiotics that I was given during the time that they were waiting for the bacterial culture to complete had just destroyed my digestive system to the point where I couldn’t take in any food or drink. I just felt sick to my stomach, I felt so sick. So they finally were able to when the culture was complete and it was proven negative, and so like I said, all they could do was determine it was sepsis caused by a virus. So I was sent home from the hospital and after a couple days my temperature was still high, but finally I was able to go home and I just wasn’t well because my digestive system was pretty well destroyed. I was weak and I had lost weight and I am very small and thin anyway. And so they took me about three-and-a-half weeks to get to the point where I was able to return to my job. I was taking probiotics and I got a different probiotic, I got one that was a much better one knowing that I had just had all of this antibiotic I got myself from our natural food store which is a really good one and really good people work there. I was recommended this very good one and so I was taking it and I was thinking that I was replenishing all of the good bacteria in my system. However, obviously I just wasn’t able to replenish it quickly enough and adequately enough and over the time I was seeing, I went to a new acupuncture doctor recommended by a friend. He was very helpful at the beginning and it seemed like I was getting stronger and better and feeling better and eating better and what not. But I started to have some, these symptoms that I didn’t understand, and when I would bring them up he would sort of say things like, “you feel that because you are so thin” or he would just sort of brush them off. So I thought, “well ok,” but at some point it was alarming to me how I was craving sugar, sweets, I was craving sweets and I have always liked sweets but I have always been able to keep it at a really nice balance with the rest of my diet. I was eating very healthfully but I was suddenly one of the symptoms was just I noticed that I was craving sweets like after every meal I wanted something sweet. I thought, “oh this is out of control, this is strange” and then I suddenly had some rashes on my legs and they got worse and worse. They looked like somewhat like eczema and my doctor, because they were sort of I guess you could call it bilateral, I had the same thing on the right as the left, my primary care physician said well when you have it on both sides equally it indicates that it is food related.
But my digestion is just getting worse and I am feeling sicker and I was losing weight because I couldn’t eat and I really came to a point where I was having pretty severe acid reflux and I really wasn’t able to eat because it was so awful. I tried, at first, after I diagnosed it, a friend loaned me a book and it’s called Sinus Survival Handbook because I was having more sinus infections which was odd to me. So she loaned me this book and she had had Candida for a long time and so I started reading it and what I read forwarded me to the chapter on Candida right away. I went to that chapter and I took the self test and I had like I don’t know, some 90, 85-90% of the symptoms. I said, “this is it,” I mean this is clearly what it is. So I immediately started researching and I started following the Candida diet but there is a lot of differences in different websites, different books that you look at. So it was very unclear to me, can I really have this? This site says yes, this site says no. So then I came down with a really serious vaginal yeast infection. So I took something that my doctor recommended which helped but it didn’t help as in certainly helpful the acid reflux and all of the other symptoms, it just cleared up the vaginal infection.
I was very thin, I was basically getting down to skin and bones, I was kind of a skeleton and I didn’t have a lot of energy and I always exercised and very active, and boy I couldn’t be so I didn’t know what to do and I just started to pray. I didn’t know where to turn. So I just started praying and my husband and I were coming home from a meditation retreat on Sunday evening and we stopped at the natural food store and I bumped into an old old friend, a woman I had done trainings with and such and in our conversation and checking in with each other I said that I was experiencing Candida and she told me she had had it for 15 years and a friend turned her on to some probiotics that have actually cleared up her Candida. So she was happy to sell me a box and so we met down from where I lived at the community center the next day and she gave me a box that, I forget exactly what, I can’t remember the name of it off the top of my head right now, but anyway it was on Robert’s website when she first bought it and she didn’t know how much, and I don’t know if it is still there, no its not, its not. So she didn’t know how much to charge me so she said she would, so I guess she looked it up on the website and he no longer had it on the website so I think she also had gotten it from Amazon. So she got the price from Amazon and she told me that she had gone to the original website and it was no longer there but she said I saw all of these other Candida products and so I requested the information on all of these products on your behalf. So great and one day somewhat there after I received in the mail this envelope filled with information on all of his Candida products and I looked through it and I said I think this is what I need, I need to try this.
Dr. Sharon Livingston: What made you feel that way? What made you say I think this is what I need?
Roselyn: Reading the description of the products like the Candida, Candiclearifies, reading what is the ingredients in the Candiclearafies and then it talks about what it would do for you, how it will heal you.
Dr. Sharon Livingston: What did it say that was so compelling to you?
Roselyn: It talked about how it actually kills off the Candida blooms and it rids your body of toxins and it also clears out heavy metals. I think you know and there may be more but I know that those are three major things. And then there was total flora 15 which is a specific to Candida probiotic and I don’t remember the others to be honest with you. I just saw there are quite a number of them. So I just said I am going to call and I done a lot of alternative healing in my life and I am very open, I am very open to it and my body responds pretty well, very well actually, to a lot of alternative healing, and actually another answer to my prayer came before I actually connected with Robert. I work for the county I live in health and human services office and one of my clients, a Latino woman who had had an accident, a head injury, came in before I had contacted Robert. Actually she was telling me that she had a healing by this woman this like an energy healing and all of her symptoms had gone away and I just said I need her number and I want to connect with her. So I did a couple of healings with this woman and she helped me actually be able to start eating. She had suggested certain things that worked initially and I was actually able to just begin eating again. But it wasn’t taking care of the acid reflux that is for sure and again I knew more it was beaded I knew that, I know my body really well and like I said I have done a lot of holistic and alternative healing and I knew that again this was another step in the right direction. But it wasn’t enough and then Robert’s information came to me. So I called the day after I got it in the mail I called and I spoke to one of the women that answered and I said told her my little story and I said I am really interested, I want to know more about these products, I think that I would like to probably start taking some of these things but I don’t even know where to begin. There is so much here and so she asked me if I would like to have a consultation with Robert and I said yes I would. So she called me back that very day, he called me later that day and I talked to him and I told him what was going on. Just his patience and his calmness, he just has a healing manner about him and you know just I am a highly sensitive person so I pick up on a lot of things that maybe others might not, but his voice and the way he talks. He said to me how old are you and I told him my age and he said how is your bone density and I said well I just had it tested this year and it is kind of on the low side but I am also a very small and very petite woman and so he said well that makes sense, but it is not usual that someone who has Candida the first product that would come up as the most important would be a calcium magnesium supplement.
It wasn’t dangerous, but OCMP would be a good product for me, it’s the most important product right then because it would balance the calcium magnesium and it would also break down the calcification. So that was good. And then the second product, I can’t remember which was second, but when he said to me which nobody had talked about and I was not going to take western medicine for it and I didn’t know what to do about the acid reflux, but he said to me and the other product that is very important for you is GI Pro which is for digestion and specifically for acid reflux. And when he said acid reflux I just was sold, I just said that is it, that is like one of the major things that I am experiencing right now is acid reflux. So I was sold right there. I knew that he was getting it, he was very humble when I said to him, “ok I am going to buy all of these products from you, I never met you, I don’t know who you are and I am putting my trust in you.” You know it was just kind of like, in this sort of question way I am putting my trust in you and he said well, he was very humble and he said something like well you know the feedback I get is very positive and he said that I am good at this, I am not perfect he wasn’t a sales man, he wasn’t trying to sell me anything at all and so I said ok, I am going to try a months worth, lets go for a month with Candiclear and with OCMP and the GI Pro and the total Flora. If I am not mistaken those are my four that I started with and I started taking them immediately that they came.
I started to see improvement pretty quickly. I started to be able to eat and feel better pretty quickly and I could call him, I could ask him questions. He was very, very patient and he didn’t rush me and he answered all of my questions very clearly very in the detail I needed, and then anytime I had to call him because of whatever that has been going on for me I have always, he has always just been there, he listens. I have been taking his supplements for a year now, I have been on the Candida diet for a year and a half and I feel pretty clean right now, I am calling next week for a consultation.
Dr. Sharon Livingston: And so what is different from a year-and-a-half ago, what is different?
Roselyn: What is different is that my skin is completely cleared up, there is no acid reflux what so ever. I am trying to think of all the symptoms that I had; I had headaches, I woke up every morning with a background headache, I don’t have headaches any longer, anxiety, I had this unexplainable anxiety that I really didn’t have control over sometimes. It wasn’t all the time, but I could sometimes wake up feeling like this anxiety for no specific reason, a non specific anxiety and that completely went away and I had lost about 8 pounds which is huge for me because, just to give you a little specifics here, I only weigh 90 pounds normally.
Dr. Sharon Livingston: Oh my goodness.
Roselyn: I am 5 feet and ½ inch to be specific and I was down to 82 pounds and it was awful. I just looked, I really looked like a skeleton, I didn’t like going out my front door because I looked so, I was so skinny. I lost all of my musculature and so I started to be able to exercise more frequently. I go to a little fitness center right by my work, I go at lunch and work out and I also walk on the days I don’t go to the gym. I do an aerobic walk and I do yoga. Also I go to a yoga studio and my ability to do these things had diminished so much and I lost all of my muscle. So I started to be able to eat better and my weight started to come up. The Candiclear is really, really excellent in helping with elimination for me. And then also Robert suggested I take five teaspoons of sesame oil. I use raw sesame oil, five teaspoons of raw sesame oil and three teaspoons of flax seed oil and I put olive oil on my salads. Every day I have those oils to help my body absorb the products better, to absorb my food better.
Dr. Sharon Livingston: Oh interesting.
Roselyn: Yeah so he said it would help in the absorption. So I have been doing that for a long time too. So yeah so it’s just been a healing journey from day one, it’s been a healing journey for me.
Dr. Sharon Livingston: That is really wonderful. Have you recommended him, have you ever recommended Robert or Get Healthy again to other people?
Roselyn: I have. I don’t talk about it to people unless it comes up, I mean its not something that you know I will bring up unless somebody asks me, you know, about what I am doing or whatever and I have given the website to a couple of people.
Dr. Sharon Livingston: Fantastic. That is great and so Roselyn that is just a wonderful wonderful story I really want to thank you for sharing it. Does he have your permission to use your, what you have said, to talk about the site and his products?
Roselyn: Yes, hope you would put it in a format, that I trust you will put it in a format that is, and like you said you would take out all the ums and ahs and all of that.
Dr. Sharon Livingston: Oh for sure. So you will sound terrific, you will sound absolutely terrific.
Roselyn: I just want to end it on a really positive note a really exciting note and you don’t have to put this in, this is for you, I mean you are welcome to use it, but that is not necessarily why I am telling you. I am telling you because I think its really exciting, I am retiring at the end of next month.
Dr. Sharon Livingston: Oh my goodness.
Roselyn: Yeah, its time and I am 64 and I will be 65 in September so I am retiring from my job and as a retirement celebration kind of a trip of a lifetime my husband he is taking a sabbatical and we are going to, and this was really important to me to get well and its been my motivation for really speeding up the process of healing, we are going to do a trek around the base of Mont Blanc and it goes through Italy and Switzerland and France.
It is very exciting and I did the training with a fitness trainer. It’s a very tiny gym, I am out in a rural area in Point Reyes California and I did a training with the fitness trainer and she gave me a program specifically because I had lost all of my musculature and my muscles are weak, and so she gave me a program to strengthen, to improve my strength and endurance and I am actually physically ready at this point to do this trek.
Dr. Sharon Livingston: Fantastic, wow.
Roselyn: All I can say is that I really honor and feel tremendous gratitude to Robert and to his commitment to finding the best products that exist and to matching them up with his clients.
Dr. Sharon Livingston: That is really wonderful to hear, yes.
Roselyn: He is just so committed, he is so, oh what word do I want, he really is committed to helping people heal; the website gethealthyagain.com really speaks for itself. He wants people, he wants to help people get healthy, he is committed to that.
Dr. Sharon Livingston: That is wonderful I think that is a good place to end and I hope you have a wonderful trip that sounds fantastic.
Roselyn: Thank you, thank you very much.

Candida, Hair Loss and Constipation Gone:

Written by a Happy Customer
Sherry had a rather embarrassing problem: she couldn’t have a normal bowel movement. She knew something was wrong because her hair was falling out, too. Long a believer in the energies that are part of us all, she was instantly attracted to Robert Harrison and his frequency-containing elixirs and other supplements. After discovering that Candida was part of her problem, she tried CandElim. Hear in her own words how she now feels in this short audio clip.
Click to play a HIGHLIGHT of this Candida relief story.

Click play on the player below to listen to the FULL testimonial now.

Disclaimer: This person’s experience is not indicative of what you will experience.

Full Testimonial Transcript

Dr. Sharon Livingston: I got your information from Robert Harrison and I was interested in talking to you and getting feedback on, I think it’s the Candida relief product that you tried?
Sherry: Right.
Dr. Sharon Livingston: So yes, I would love to hear all about that.
Sherry: Well as you know I had it and it was causing me not to have bowel movements.
Dr. Sharon Livingston: Wow.
Sherry: And I think I was on it for 2 months.
Dr. Sharon Livingston: So before you tell me that part, how did you come to Robert’s site? How did you find that?
Sherry: I am into healthy stuff and I just looked up on the Internet and I got reading his stuff and I was impressed. Then I muscle test. You can muscle test to calibrate to see what is truth and what is not and he showed very high. So I said, “I am going to try it” and I did. My sister passed and I wanted him to work on me because of the simple fact that I had been under so much stress for her because I was caring for her.
Dr. Sharon Livingston: Sure.
Sherry: I knew I had some problems but my mind was so messed up and he said one of your problems is Candida toxins and I said “ok, let’s get rid of it.” So he got me on the product.
Dr. Sharon Livingston: Which one was it?
Sherry: Oh goodness let me see if I have the bottle, I don’t remember if I kept them, I like his elixirs you know.
Dr. Sharon Livingston: The elixirs?
Sherry: Yes, I love those.
Dr. Sharon Livingston: What do you like about his elixirs?
Sherry: Because there are frequencies and I believe in frequencies 100%, the energy, you know, because I do a lot of energy work and so I really believe in that part. But the bottle that I was taking (I am going to spell it for you so you have the correct it) is Candelim.
Dr. Sharon Livingston: Candelim.
Sherry: Yeah and I used that. I used that for 2 months, actually 3 months, but 2 months it was gone and then the last month was to make sure we just got everything; none was hiding

Galantamine

Galantamine

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Galantamine
Galantamine.svg
Galantamine ball-and-stick.png
Clinical data
Trade namesRazadyne
AHFS/Drugs.comMonograph
MedlinePlusa699058
Pregnancy
category
  • B
Routes of
administration
Oral
ATC code
Legal status
Legal status
  • In general: ℞ (Prescription only)
Pharmacokinetic data
Bioavailability80 to 100%
Protein binding18%
MetabolismHepatic partially CYP450:CYP2D6/3A4 substrate
Biological half-life7 hours
ExcretionRenal (95%, of which 32% unchanged), fecal (5%)
Identifiers
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
PDB ligand
ECHA InfoCard100.118.289
Chemical and physical data
FormulaC17H21NO3
Molar mass287.354 g/mol
3D model (JSmol)
Melting point126.5 °C (259.7 °F)
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Galantamine (Nivalin, Razadyne, Razadyne ER, Reminyl, Lycoremine) is used for the treatment of mild to moderate Alzheimer's disease and various other memory impairments, in particular those of vascular origin. It is an alkaloid that has been isolated from the bulbs and flowers of Galanthus caucasicus (Caucasian snowdrop), Galanthus woronowii (Voronov's snowdrop), and some other members of the family Amaryllidaceae such as Narcissus (daffodil), Leucojum aestivum (snowflake), and Lycoris including Lycoris radiata (red spider lily).[1] It can also be produced synthetically.
Studies of usage in modern medicine began in the Soviet Union in the 1950s. The active ingredient was extracted, identified, and studied, in particular in relation to its acetylcholinesterase (AChE)-inhibiting properties. The bulk of the work was carried out by Soviet pharmacologists M. D. Mashkovsky and R. P. Kruglikova–Lvova, beginning in 1951.[2] The work of Mashkovsky and Kruglikova-Lvova was the first published work that demonstrated the AChE-inhibiting properties of galantamine.[3]
The first industrial process was developed in Bulgaria by prof. Paskov in 1959 (Nivalin, Sopharma) from a species traditionally used as a popular medicine in Eastern Europe, and, thus, the idea for developing a medicine from these species seems to be based on the local use (i.e., an ethnobotany-driven drug discovery).[4][5]
In addition to uses in Alzheimer's disease, galantamine has been used to treat myasthenia, myopathy, muscular dystrophy, and sensory and motor dysfunction associated with disorders of the central nervous system. Research has indicated that galantamine may prove useful both in the treatment of organophosphate poisoning and in the treatment of autism in children and adolescents.


Uses in mythology[edit]

In Homer's Odyssey the god Hermes gives Odysseus an herb with "a black root, but milklike flower" called "moly", which Hermes claims will make Odysseus immune to the sorceress Cerce's drugs. It is believed that moly is the snowdrop Galanthus nivalis, which is a source of galantamine.[6] The descriptions of moly given by Greek physician and herbalist Dioscorides support moly's identity as Galanthus nivalis.[6] It has been proposed that the drugs Cerce used were an extract from Datura stramonium (also known as jimsonweed), which causes memory loss and delirium.[6] This would give a basis for the snowdrop's use as an antidote, as Datura stramonium is anticholinergic, while galantamine is an acetylcholinesterase inhibitor.[6]

Medical uses[edit]

Galantamine
Uses
treatment of dementia caused by Alzheimer's disease[7]
Who might take
adults who have mid-to-moderate Alzheimer's disease as indicated by the Mini–mental state examination[7]
Precautions
Other options
Galantamine is indicated for the treatment of mild to moderate vascular dementia and Alzheimer's.[8][9] In the US, it is approved by the Food and Drug Administration for the treatment of Alzheimer's disease. In Austria the drug is approved for muscular dystrophy. Research has indicated that galantamine may also prove useful in the treatment of organophosphate poisoning.[10] Galantamine has been used in Eastern Europe to treat neuromuscular diseases including muscular dystrophy and myasthenia, however this has not lead to widespread use.[11]

Alzheimer's disease[edit]

Alzheimer's disease is characterized by the impairment of cholinergic function. One hypothesis is that this impairment contributes to the cognitive deficits caused by the disease. This hypothesis forms the basis for galantamine's use as a cholinergic enhancer in the treatment of Alzheimer's. Galantamine completely inhibits acetylcholinesterase, an enzyme which hydrolyzes acetylcholine. As a result of acetylcholinesterase inhibition, galantamine increases the availability of acetylcholine for synaptic transmission.[12] Additionally, galantamine binds to the allosteric sites of nicotinic receptors, which causes a conformational change.[13] This allosteric modulation increases the nicotinic receptor's response to acetylcholine.[12] The activation of presynaptic nicotinic receptors increases the release of acetylcholine, further increasing the availability of acetylcholine.[12] Galantamine's competitive inhibition of acetylcholinesterase and allosteric nicotinic modulation serves as a dual mechanism of action.[13]
To reduce the prevalence of negative side effects associated with galantamine, such as nausea and vomiting, a dose-escalation scheme may be used.[14] The use of a dose-escalation scheme has been well accepted in countries where galantamine is used.[14] A dose-escalation scheme for Alzheimer's treatment involves a recommended starting dosage of 4mg galantamine tablets given twice a day (8 mg/day).[15] After a minimum of 4 weeks, the dosage may then be increased to 8 mg given twice a day (16 mg/day).[15] After a minimum of 4 weeks at 16 mg/day, the treatment may be increased to 12 mg given twice a day (24 mg/day).[15] Dosage increases are based upon the assessment of clinical benefit as well as tolerability of the previous dosage.[15] If treatment is interrupted for more than three days, the process is usually restarted, beginning at the starting dosage, and re-escalating to the current dose.[15]

Available forms[edit]

The product is supplied in both a prescription form as well as an over the counter supplement in twice-a-day tablets, in once-a-day extended-release capsules, and in oral solution.

Side effects[edit]

Galantamine's side effect profile was very similar to that of other cholinesterase inhibitors, with gastrointestinal symptoms being the most notable and most commonly observed. One study reports higher proportions of patients treated with galantamine experiencing nausea and vomiting as opposed to the placebo group.[14] Another study using a dose-escalation treatment has found that incidences of nausea would decrease to baseline levels soon after each increase in administered dosage.[13] In practice, some other cholinesterase inhibitors might be better tolerated; however, a careful and gradual titration over more than three months may lead to equivalent long-term tolerability.[16]
The U.S. Food and Drug Administration (FDA) and international health authorities have published an alert of galantamine based on data from two studies during the treatment for mild cognitive impairment (MCI); higher mortality rates were seen in drug-treated patients.[17][18] On April 27, 2006, FDA approved labeling changes concerning all form of galantamine preparations (liquid, regular tablets, and extended release tablets) warning of the risk of bradycardia (slow resting heart rate), and sometimes atrioventricular block, especially in predisposed persons. At the same time, the risk of syncope (fainting) seems to be increased relative to placebo. "In randomized controlled trials, bradycardia was reported more frequently in galantamine-treated patients than in placebo-treated patients, but was rarely severe and rarely led to treatment discontinuation"[19] These side effects have not been reported in Alzheimer's Disease related studies.[20]

Pharmacology[edit]

Galantamine's chemical structure contains a tertiary amine. At a neutral pH, this tertiary amine will often bond to a hydrogen, and appear mostly as an ammonium ion.[11]
Galantamine is a potent allosteric potentiating ligand of human nicotinic acetylcholine receptors (nAChRs) α4β2, α3β4, and α6β4, and chicken/mouse nAChRs α7/5-HT3 in certain areas of the brain.[21] By binding to the allosteric site of the nAChRs, a conformational change occurs which increases the receptors response to acetylcholine.[12] This modulation of the nicotinic cholinergic receptors on cholinergic neurons in turn causes an increase in the amount of acetylcholine released.[22] Galantamine also works as a weak competitive and reversible cholinesterase inhibitor in all areas of the body.[21] By inhibiting acetylcholinesterase, it increases the concentration and thereby action of acetylcholine in certain parts of the brain. Galantamine's effects on nAChRs and complementary acetylcholinesterase inhibition make up a dual mechanism of action. It is hypothesized that this action might relieve some of the symptoms of Alzheimer's.
Galantamine's dual mechanism of action
Galantamine in its pure form is a white powder. The atomic resolution 3D structure of the complex of galantamine and its target, acetylcholinesterase, was determined by X-ray crystallography in 1999 (PDB code: 1DX6; see complex).[23] There is no evidence that galantamine alters the course of the underlying dementing process.[24]

Pharmacokinetics[edit]

Absorption of galantamine is rapid and complete and shows linear pharmacokinetics. It is well absorbed with absolute oral bioavailability between 80 and 100%. It has a half-life of seven hours. Peak effect of inhibiting acetylcholinesterase was achieved about one hour after a single oral dose of 8 mg in some healthy volunteers.
The coadministration of food delays the rate of galantamine absorption, but does not affect the extent of absorption.[13]
Plasma protein binding of galantamine is about 18%, which is relatively low.

Metabolism[edit]

Approximately 75% of a dose of galantamine is metabolised in the liver. In vitro studies have shown that Hepatic CYP2D6 and CYP3A4 are involved in galantamine metabolism. Within 24 hours of intravenous or oral administration approximately 20% of a dose of galantamine will be excreted unreacted in the urine.[13]
In humans, several metabolic pathways for galantamine exist.[25] These pathways lead to the formation of a number of different metabolites.[25] One of the metabolites that may result can be formed through the glucuronidation of galantamine.[25] Additionally, galantamine may undergo oxidation or demethylation at its nitrogen atom, forming two other possible metabolites.[25] Galantamine can undergo demethylation at its oxygen atom, forming an intermediate which can then undergo glucuronidation or sulfate conjugation.[25] Lastly, galantamine may be oxidized and then reduced before finally undergoing demethylation or oxidation at its nitrogen atom, or demethylation and subsequent glucuronidation at its oxygen atom.[25]
Metabolic pathways of galantamine
For Razadyne ER, the once-a-day formulation, CYP2D6 poor metabolizers had drug exposures that were approximately 50% higher than for extensive metabolizers. About 7% of the population has this genetic mutation; however, because the drug is individually titrated to tolerability, no specific dosage adjustment is necessary for this population.

Drug interactions[edit]

Since galantamine in metabolized by CYP2D6 and CYP3A4, inhibiting either of these isoenzymes will increase the cholinergic effects of galantamine.[13] Inhibiting these enzymes may lead to adverse effects.[13] It was found that paroxetine, an inhibitor of CYP2D6, increased the bioavailability of galantamine by 40%.[13] The CYP3A4 inhibitors ketoconazole and erythromycin increased the bioavailability of galantamine by 30% and 12%, respectively.[13]

Synthesis[edit]

Galantamine is produced from natural resources and a patented total synthesis process. Many other synthetic methods exist but have not been implemented on an industrial scale.

Research[edit]

Organophosphate poisoning[edit]

The toxicity of organophosphates results primarily from their action as irreversible inhibitors of acetylcholinesterase.[10] Inhibiting acetylcholinesterase causes an increase in acetylcholine, as the enzyme is no longer available to catalyze its breakdown.[10] In the peripheral nervous system, acetylcholine accumulation can cause an overstimulation of muscarinic receptors followed by a desensitization of nicotinic receptors.[10] This leads to severe skeletal muscle fasciculations (involuntary contractions).[10] The effects on the central nervous system include anxiety, restlessness, confusion, ataxia, tremors, seizures, cardiorespiratory paralysis, and coma.[10] As a reversible acetylcholinesterase inhibitor, galantamine has the potential to serve as an effective organophosphate poisoning treatment by preventing irreversible acetylcholinesterase inhibition.[10] Additionally, galantamine has anticonvulsant properties which may make it even more desirable as an antidote.[10]
Research supported in part by the US Army has led to a US patent application for the use of galantamine and/or its derivatives for treatment of organophosphate poisoning. The indications for use of galantamine in the patent application include poisoning by nerve agents "including but not limited to soman, sarin, and VX, tabun, and Novichok agents". Galantamine was studied in the research cited in the patent application for use along with the well-recognized nerve agent antidote atropine. According to the investigators, an unexpected synergistic interaction occurred between galantamine and atropine in an amount of 6 mg/kg or higher. Increasing the dose of galantamine from 5 to 8 mg/kg decreased the dose of atropine needed to protect experimental animals from the toxicity of soman in dosages 1.5.times the dose generally required to kill half the experimental animals.[26]

Autism[edit]

Galantamine given in addition to risperidone to autistic children has been shown to improve some of the symptoms of autism such as irritability, lethargy, and social withdrawal.[27] Additionally, the cholinergic and nicotinic receptors are believed to play a role in attentional processes.[28] Some studies have noted that cholinergic and nicotinic treatments have improved attention in autistic children.[28] As such, it is hypothesized that galantamine's dual action mechanism might have a similar effect in treating autistic children and adolescents.[28]

Anesthesia[edit]

Galantamine may have some limited use in reducing the side-effects of anesthetics ketalar and diazepam. In one study, a control group of patients were given ketalar and diazepam and underwent anesthesia and surgery.[29] The experimental group was given ketalar, diazepam, and nivalin (of which the active ingredient is galantamine).[29] The degree of drowsiness and disorientation of the two groups was then assessed 5, 10, 15, 30 and 60 minutes after surgery.[29] The group that had taken nivalin were found to be more alert 5, 10, and 15 minutes after the surgery.[29]

References[edit]

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External links[edit]