Wednesday 31 July 2013

18 years old- they have got it so wrong

Another example of why the need to stay off MSS site and explore the alternatives , there are many many young adults incorrectly diagnosed, all over the world, IT HAS TO STOP
 
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18 with ms
Author
Post
19 Jul 2013 at 2:58AM
Hey im 18 (nearly 19)
I've been struggling lately and I didn't know who to talk to but when I seen there was forums on this website I thought it was a great way to support others and be supported.
Would love to hear about different peoples experiences and be able to talk to someone how knows what im going through that isn't a ms specialist hehe
Thank you, Tasha x
19 Jul 2013 at 4:03PM
Hey Tasha,
If you need somebody to talk to please don't hesitate in calling our helpline on 0808 800 8000...
Are you not getting much support at home?
Stewart (admin)
19 Jul 2013 at 4:26PM
My boyfriend helps me but I feel bad for unloading this all on him. Ave tried to her help from the Hospital but there so busy that I haven't received any yet.
Thank you, Tasha x
26 Jul 2013 at 11:48AM
Hi Tasha,
My names Ross, I'm 23, nearly 24 and I was diagnosed with MS when I was 16.
I know exactly what your going through and it's not the easiest of things to go through. If you'd like to chat about anything ust send me a message. Hope I can help.
x
30 Jul 2013 at 12:39PM
Hi Tasha welcome to the forum, so sorry that you have been given this diagnosis and at such a young age, we are all here and if you've any questions don't hesitate to ask, whatever it may be.
There is a section for young people with ms maybe introduce yourself there, but us oldies lol will bely too willing to jhelp.x
30 Jul 2013 at 12:41PM
Apologies your already in the young section, blame me age and this flaming,ipad lol.

Tuesday 30 July 2013

MS society UK statement is incorrect in my opinion

  • And because of following statement, is why it is a dangerous place to go, to be convinced by others about a condition that  in my opinion does not exist, the MS Society is fueling the fire and have done for years. 
    Why do you think so many are in "denial" because it doesn't make any sense.


    What is MS | Multiple Sclerosis Society UK
    Information about multiple sclerosis (MS) including causes, early signs, diagnosis
    , symptoms, treatments and therapies.
    www.mssociety.org.uk/what-is-ms

Sunday 28 July 2013

Iron obesity Candida and Thyroid

The information contained in this groundbreaking article applies to at least 75 percent of people who are struggling to lose weight. It is a major factor contributing to the fatigue associated with being overweight and having symptoms of hypothyroid. It involves new discoveries regarding iron metabolism and explains why even if you eat foods containing plenty of iron you may still have rather dramatic iron deficiency issues, which handicap your metabolism and thyroid function. 
Traditional thinking about iron is that either you get enough in your diet or you don’t. People who don’t eat red meat, menstruating women, those who exercise a lot, and those with digestive bleeding or other blood loss issues are at risk for iron deficiency and either functional or blatant anemia. In general, iron deficiency is thought to be associated with undernutrition or malnourishment.
Ironically, in the past few years it has become clear that at least half the people who are overweight have impaired iron metabolism detectable on blood tests. In many of these cases dietary iron intake was adequate, perplexing researchers. It now appears that inflammation associated with excess body weight elevates a hormone in your liver called hepcidin, which has the net effect of reducing iron absorption into your body from your digestive tract. The result is a metabolic nightmare of weight gain, fatigue, and poor thyroid function.

Hepcidin 101

Hepcidin is a hormone produced in your liver, discovered in 2000. Scientists discovered that it regulates iron use throughout your body (iron homeostasis). One of the ways in which hepcidin regulates iron status is by deciding how much iron to let into your body. In essence, it communicates directly to the cells of your digestive tract, either allowing them to let iron in or not. High levels of hepcidin reduce or prevent dietary iron intake, regardless of the iron content of your food.
It is now clear that hepcidin levels elevate in response to inflammation. This could be from inflammation of any type: infection, toxin exposure, excess alcohol, medications, injury, excess exercise, lack of sleep, too much stress, etc. In this regard, being overweight is an ongoing inflammatory problem wherein your extra pounds of white adipose tissue crank out inflammatory signals 24 hours a day, seven days a week, as if someone will not stop yelling at you. The more excess weight you have, the higher the inflammation (in addition to all other potential sources of inflammation).
Iron is utterly indispensable to your metabolism and survival. For example, mice that are genetically bred to have high levels of hepcidin die within a few days from iron deficiency. Iron is need for growth, repair, assembly of proteins into your body structures, nerve function, and much more. 
On the other hand, iron is highly reactive. Your body literally keeps it in cages like ferritin, similar to a lion at the zoo. When needed, the lion is let out at the proper place and time so that it can do something useful. If the cage is opened at the wrong time or place, iron can jump out and set off damaging free radical chain reactions. It appears that hepcidin intentionally reduces iron intake during times of inflammatory stress to prevent the inflammation from damaging iron transport and storage systems (causing inappropriate iron release). In other words, if your body is in a state of inflammatory wear and tear it may be difficult to use iron in a healthy way.
This offers excellent survival features for short-term inflammatory distress. However, a chronically inflamed person, as from obesity, can develop a real catch-22 wherein hepcidin is elevated for too long, creating a scenario of ongoing iron deficiency, either functional (meaning not enough iron for metabolism to function well) or blatant (meaning anemia). 
Rampant overuse of antibiotics and high-sugar diets have created an epidemic of candida albicans overgrowth in overweight people. This is especially common in overweight people with thyroid problems, as I have observed first hand since 1985. Interestingly, hepcidin is a powerful antifungal. This means that your body may raise hepcidin levels as part of its natural defense against candida overgrowth. Again, this has survival advantages, especially in olden times. However, in a population of overweight people with antibiotic-induced candida overgrowth, it is a double whammy against functional metabolism.

The Impact of Low Iron on Metabolism

A new study details the dire metabolic consequences of low iron status. It shows that low iron turns on genes in your liver and muscles that promote fat storage and cause abnormal blood sugar elevation – precisely what goes wrong with metabolism that leads to the metabolic syndrome.
The consequence to thyroid metabolism is twofold. First, the inactive thyroid hormone, T4, is converted to the biologically active hormone, T3, mostly on cell membranes of liver cells. Hepcidin is made in your liver and is produced excessively in response to high inflammation. Such inflammation will also damage liver cell membranes, thus reducing the conversion of T4 to T3. This is one main reason why inflammation of any type disturbs thyroid function.
Second, when biologically active thyroid, T3, binds to cell membranes and communicates to the nucleus of your cells how fast their metabolic pace should be set, it is like a hormone manager giving an order to a cell factory. The worker bees in the cell factory then need iron for the genes that will implement the thyroid order. In fact, the next 80 metabolic genes responding to a thyroid order all need iron. If iron is lacking, metabolism simply cannot run at an optimal pace, resulting in all the symptoms of hypothyroid—even in the presence of normal T4 and normal T3.
Even if iron is normal on a blood test, a person can still have all the problems above, though levels tend to be toward the lower end of the normal range. Hemoglobin (Hgb) and hematocrit (Hct) are also on the low side of the normal with this problem. One or another being out of range or on the low side signifies a major problem. Serum ferritin is typically low or low normal, unless inflammation is very high, which can actually drive up ferritin scores. Lab tests can help; however, fatigue along with trouble losing weight despite eating better and exercising are general indicators of a potential problem. 
 

Solving Iron Deficiency Relating to Stubborn Weight

Adequate iron intake (red meat) compared to obvious iron loss (menstrual cycles, etc.) is still important to understand. However, this new data says that a condition of less inflammation must exist in order for iron to work properly in your body.
The most basic approach is to follow The Leptin Diet®, which is anti-inflammatory. As you begin to lose weight, you reduce inflammation, hepcidin levels should come down, and the iron in your diet will work better. If you have little iron in your diet, you should take a high-quality iron supplement. I like iron glycinate, a true protein chelate of iron. I would stay away from all cheap iron salts such as ferrous sulfate (these cause free radical damage).
There are many basic supplements that are fundamental to metabolism along with a good diet, as I have outlined in The Leptin Diet Weight Loss Challenge #1 – Overview and Basic Needs. All of these are significantly contribute to anti-inflammatory basic nutrition. Based on the new information in this article, it is accurate to say that ensuring you have adequate iron intake should be added to this basic list of nutrient needs for weight loss, especially in conjunction with basic anti-inflammatory nutrition.
A more comprehensive approach to this specific issue is to take an iron supplement as a trial to see if it helps your energy. Additionally, fat-soluble antioxidants that are targeted to improve liver function would be top choices. My top recommendations would be acetyl-l-carnitine, coenzyme Q10, tocotrienol E, r-alpha lipoic acid, and silymarin. Many other anti-inflammatory nutrients may also be of value. Your bottom line is to get enough support to engage the process of weight loss, maintain steady progress, improve your energy level, and direct your hemoglobin and hematocrit levels to the middle of the normal range on a blood test.
Some individuals may need to employ a more targeted anti-candida program to fully solve this problem. I discuss these topics more fully in my series of comprehensive articles on the Leptin Diet Weight Loss Challenge. It is important to know the direction you are heading. If you are doing well and making progress, you are most likely doing enough – at least as long as you are getting somewhere. If you hit a plateau or fail to get out of the starting block, you certainly need to become an active problem solver for your metabolic issues. Hepcidin issues are far more common than not in any person who struggles with weight.

Summary

Your body handles iron as a top priority, since it is both vital to survival and potentially problematic. Iron is essential for proper metabolism, including normal thyroid activation and cellular function. Obesity-induced inflammation elevates a hormone called hepcidin, which has the unfortunate side effect of disrupting iron metabolism in your body. This mechanism helps you overcome short-term inflammation and was very handy in olden times for survival purposes. In modern times, especially in a population of overweight people who often have candida issues, it can viciously lock malfunctioning metabolism in place. Solving the problem requires adequate iron intake, along with a reduction in inflammation. Reducing life stress helps. Sleeping better helps. Following The Leptin Diet® also helps. Many dietary supplements also help reduce inflammation. Especially important are fat-soluble antioxidants that help reduce inflammation in the liver (the place of hepcidin synthesis). Use enough support to feel a difference in your energy level, while engaging and sustaining the process of healthy weight loss. There is a path to a healthier you!

Candida and obesity

Candidiasis

The Facts on Candidiasis

Candidiasis, also called thrush or moniliasis, is a yeast infection. Candida albicans is an organism that normally makes a quiet home for itself on your skin and doesn't bother anyone. We all carry this organism on our skin, in our mouth, in our gastrointestinal tract (gut), and, in the case of women, in the vagina.
Occasionally the yeast multiplies uncontrollably, causing pain and inflammation. Candidiasis may affect the skin. This includes the external surface skin and the skin of the vagina, the penis, and the mouth. Candidiasis may also infect the blood stream or internal organs such as the liver or spleen. By far the most common problems are skin, mouth and vaginal infections. It also is a common cause of diaper rash. These can be bothersome infections, but are not life threatening.
Candidiasis can kill if it reaches the bloodstream or vital organs such as the heart, but this is rare even in people with damaged immune systems and is almost unheard of in healthy people. Nevertheless, candidiasis is a constant nuisance, and sometimes a serious threat to people with AIDS and some cancer patients who lack the immune resources to fight it.

Causes of Candidiasis

You don't catch candidiasis. The yeast is already there. A number of factors can increase the chance of the yeast growing out of control. The leading cause is overuse of antibiotics. Yeast must compete for the right to live on us with various other organisms, many of them bacteria. These bacteria, which live on the skin and in the intestine and vagina, among other places, are harmless but good at fighting off yeast. When we take antibiotics to deal with less friendly bacteria, we kill off these harmless ones as well. Yeast, which is unaffected by antibiotics, moves into the vacated spots once occupied by bacteria, and starts to grow and multiply.
Steroids and some cancer medications weaken the immune system and can allow yeast to flourish. Candida albicans infections of the mouth (known as oral thrush) most often develop in people with diseases such as cancer and AIDS. They can also develop in people with diabetes or in people who have long-term irritation resulting from dentures. Taking birth control pills increases your chances of getting vaginal candidiasis. Hot weather and tight clothing are also risk factors, as they create the ideal environment for candida.
Other conditions that tend to encourage yeast include obesity and pregnancy. Yeast generally infects intertriginous areas, that is, areas where skin contacts skin. Overweight people have more folds in their skin. They also sweat more, and Candida albicans is fond of moist skin. Pregnancy causes temporary obesity and may weaken the immune system, increasing the risk of yeast infections.
Experts disagree on the question of sexual transmission. Some research has suggested that it's very unlikely for an infected woman to give a man candidiasis. On the other hand, it's not unlikely that a man could give candidiasis back to his partner once he has it. Recent research has actually found Candida albicans in the sperm of men whose partners suffered from recurrent yeast infections. You should be aware of this possibility if a yeast infection keeps coming back.

Do you have psoriasis? How bad it is? Learn more.


Symptoms and Complications of Candidiasis

A candida infection of the skin appears as a clearly defined patch of red, itchy skin, often leaking fluid. Scabs and pustules may be seen around the edge of the rash. It will usually be found in areas such as the groin, the folds of the buttocks, between the breasts, toes, or fingers, and in the navel.
A vaginal yeast infection may well result in a slow leakage of a thick, white, cheese-like substance. The vagina may itch or burn, especially during urination or sex. Pain or discomfort during intercourse is common.
Candidal paronychia is candidiasis of the fingernails. It often strikes people whose hands are in water a lot. Sometimes it presents as a painful, red, swollen area around the fingernail. In worse cases, the fingernail may separate, revealing a discoloured white or yellow nail bed.

The diabetes and Thrush

Thrush

Thrush is the most common form of yeast infection Thrush is the most common form of yeast infection
Thrush is a yeast infection (candida albicans) which tends to affect warm, moist areas of the body such as the vagina, penis, mouth and certain areas of skin.
Thrush is more common in people with diabetes as high sugar levels lead to better conditions for the yeast to grow.
A dry mouth coupled with a higher amount of glucose in the saliva can also make for favourable conditions for thrush.

What causes thrush?

High blood sugar levels is one of the main causes of thrush and so is an weakened immune system, which is also common in people with diabetes.
Damaged or irritated skin also promotes the growth of thrush.
Smoking increases the chance of oral thrush and certain oral contraceptives may cause vaginal thrush.

Symptoms of thrush


Vaginal thrush (vulvovaginal candidiasis) symptoms include:
  • Soreness and irritation
  • White curd appearance on the skin
  • Pain during sexual intercourse
  • White vaginal discharge
  • Reddening of the vulva the outer parts of the vagina)
  • Itching around the vagina (infectious vaginitis)
Oral thrush (oral candidiasis) symptoms include:
  • A nasty or bitter taste
  • Redness or bleeding inside the mouth
  • Creamy white coloured patches (lesions) in the mouth (cheeks, lips, tongue or the back of the mouth)
  • Painful and sore mouth (can include the throat)
  • Cracks

Candida and diabetes connection


What is Diabetes?

Diabetes is a characterized by "high blood sugar levels" in the body, which is often referred to as hyperglycemia, as opposed to hypoglycemia which is consistently "low blood sugar levels". There are two types of diabetes: diabetes insipidus and diabetes mellitus.
Diabetes insipidus is a rare disorder caused by a deficiency of the pituitary hormone, which is usually the result of damage.
Diabetes mellitus results from the production of insufficient amounts of insulin by the pancreas. Without insulin the body cannot utilize glucose, thus creating a high level of glucose in the blood, and a low level of glucose absorption by the tissues. Diabetes mellitus is generally divided into two categories: Type I, called insulin-dependent or juvenile diabetes, and Type II in which the onset of the diabetes occurs during adult-hood.1
This article will concentrate on Type II diabetes, often referred to the maturity-onset diabetes. It is caused by either inadequate pancreas function or the inability of the body to use insulin efficiently.
Sometimes, a shortage of insulin-receptor cells (sites throughout the body where the interaction of glucose and insulin occurs) allows the insulin to be present in the bloodstream without working properly, which is also called "insulin resistance". This results in high blood sugar levels which places a great strain on other organs in the body. 1
It may evolve from a gradual slowing of insulin production with the pancreas and other disorders of the endocrine system which may cause hormonal imbalances that disturb glucose regulation.
Symptoms of Type I diabetes are excessive thirst and urination, fatigue, altered vision, fainting, irritability, and slow healing of cuts and bruises. The same symptoms may signal Type II diabetes, or no symptoms may appear at all. Type II is characterized by blurred vision, itching, unusual thirst, drowsiness, fatigue, skin infections, slow healing, and tingling or numbness in the feet. Onset of the symptoms is usually later in life. 2
Diet often controls Type II diabetes and insulin is not usually required. Studies indicate that it is due to impaired glucose tolerance that may lead to full-blown diabetes.1
Other signs of diabetes include lingering flu-like symptoms, loss of hair on the legs, increased facial hair, small yellow bumps anywhere on the body (known as xanthomas-cholesterol, which are raised, waxy-appearing skin lesions), and inflammation of the penile skin.1
If the Type II diabetic exercises greater care in food choices and carefully reads food labels, he will be able to control the problem and avoid drugs or insulin.2 Diabetes and hypoglycemia are basically related to insulin problems, and they both respond to the same kind of dietary guidelines.4

Diabetic Symptoms are Your Body's Attempt to Heal Itself

What happens if you dam a stream and create a pond? Some days you've got larvae and algae (fungi) growing. If the stream is moving, you are fine.
You need a constant stream of mucus to get rid of and prevent an infection. In almost all cases if you treat a symptom you are going to make the disease worse because the symptom is there as your body's attempt to heal itself.9
Now, the medical profession is continuously segregating more and more symptoms into diseases, they call the symptoms diseases. So they treat what they think is the disease which is just a symptom.8
The problem is that medicine really isn't a science, it is a business.9

What is the Purpose of Insulin?

If you ask your doctor, they will say that it is to lower blood sugar, but that is a trivial side effect. Insulin's evolutionary purpose, among others known right now, is to "store excess nutrients".
When your body notices that the sugar is elevated, it is a sign that you've got more than you need right now, so it is accumulating in your blood. So insulin will be released to take that sugar and store it. How does it store it?

How Insulin Stores Nutrients

Insulin stores nutrients in the form of glycogen, which is the principal carbohydrate storage material in animals, which occurs mainly in the liver, in muscles, and in fungi and yeasts.
But you have very little in your body at any one time. All the glycogen stored in your liver and muscles, etc. wouldn't last you a day if you were active. Once you fill up your glycogen stores, the excess sugars and carbohydrates are stored as a particular kind of triglyceride, or fatty acid, which consists of palmitic acid and saturated fat.
So the idea by the medical profession of going on a high complex carb, low saturated-fat diet is an absolute oxymoron (self-contradictory effect), because those high complex carb diets are nothing but a high glucose diet, or high sugar diet, and your body is just going to store it as saturated fat, which is body fat.9
Insulin doesn't just store carbs. It is an anabolic* hormone, which increases the storage of glucose, fatty acids and amino acids in cells and tissues. Body builders are injecting themselves with insulin now, because it is legal, and because it builds muscle and it stores protein too.
*anabolic means occurring inside the body, where it builds more complex substances from simpler ones.
A lesser known fact is that insulin also stores magnesium. It also plays a role in vitamin C and it stores all sorts of nutrients. But what happens if your cells become resistant to insulin? First of all you can't store magnesium so you lose it, and you lose it out the urine. 9

Magnesium's Major Roles

See 10. Intracellular magnesium relaxes muscles. When you can't store magnesium because the cell is resistant you lose magnesium and your blood vessels constrict. This increases blood pressure, and reduces energy since intracellular magnesium is required for all energy producing reactions that take place in the cell. But magnesium is also necessary for the action of insulin and for the manufacture of insulin.
So when your insulin is raised you lose magnesium and the cells become even more insulin resistant. Blood vessels constrict, glucose and insulin can't get to the tissues, and that makes them more insulin resistant, so the insulin levels go up and you lose more magnesium. It is a vicious cycle.
What's more this starts before you were born. Insulin sensitivity is going to start from the moment the sperm combines with the egg. If your mother while you were in the womb was eating a high carb diet, which is turning into sugar, it follows that you will be born with insulin resistance.
Does that mean it is genetic? No, you can be born with something and it doesn't mean it is genetic. Diabetes is not a genetic disease as such. It is caused by diet.
Insulin also causes retention of sodium, which causes water retention, which causes high blood pressure which causes congestive heart failure. One of the strongest stimulants of the sympathetic nervous system is high levels of insulin.
The immediate effects of raising blood sugar from a high carb meal, is to raise insulin and that immediately triggers the sympathetic nervous system which will cause spasms and constriction of the arteries.

How Cells become Insulin Resistant10

Cells become insulin resistant because they are trying to protect themselves from the toxic effects of high insulin. They down regulate their receptor activity and the number of their receptors so they don't have to listen to that noxious stimuli all the time.
So the pancreas puts out more insulin, but the cells are not responding no matter how much it produces. But the pancreas cannot keep that up forever without breaking down.

What Cells Become Insulin Resistant First?10

If all of the cells were resistant to excess insulin we wouldn't have a problem, but not all cells become resistant.
The liver becomes resistant first, then the muscle tissue, then the fat [body]. When the liver becomes resistant it responds by suppressing the production of sugar. Sugar comes from two areas. What you have eaten and from your liver.
If your liver is listening to insulin properly it won't make much sugar. If your liver is resistant, those brakes are lifted and your liver starts making a bunch of sugar.
What is the action of insulin in muscles? It allows your muscles to burn sugar for one thing. If your muscles become resistant to insulin it can't burn the sugar just manufactured by the liver. The liver is producing too much, which the muscles can't burn, and it raises your blood sugar.
It takes fat cells a lot longer to become insulin resistant. What is the action of insulin on your fat cells? It is to store that fat. It takes sugar and it stores it as fat, so until your fat cells become resistant you get fat, and that is what you see.
As people become more and more insulin resistant, they get fat and their weight goes up. They will plateau at a certain weight. For some it is 300 pounds, for others it is one hundred and fifty pounds. Eventually they plateau as the fat cells protect themselves and become insulin resistant.
All the while your pancreas is putting out more insulin to compensate.

Some Tissues Don't Become Insulin Resistant10

However, the lining of the arteries do not become resistant very readily. All of that insulin is affecting the lining of your arteries, which are loading up with plaque. Insulin floating around in the blood causes a plaque build-up.
There are many studies that prove this is happening so it is hard to understand why the blame is put on cholesterol and saturated fats.
Insulin also causes blood to clot, affects the bones, and it controls growth hormone.

How to Stop or Control the Rate of Insulin Resistance10

The rate at which our cells become insulin resistant can be controlled by diet. It starts by eliminating certain carbs which act just like sugar in the body, i.e. starches, grains, and by eliminating sugars, including fruit.
Therefore it stands to reason that a low-carb diet will create less insulin resistance by the cells.
It is obvious by the above information that curing diabetes is related to insulin resistance and that insulin production and resistance can be controlled by diet.
Therefore curing candida and diabetes starts with same the diet, which consists of moderate protein, high "good" fats and low carbs, and no starches and sugars.
Also, the elimination of toxins in the diet and the environment are also important for overall body health. This means eliminating soy and all soybean based products, "bad" fats and oils, processed foods, and all of the other toxic sources talked about in the article How to Successfully Overcome Candida.
A healthy diet, with adequate nutrients, is necessary for maintaining an effective immune system as well. Dietary changes recommended are not only useful for continued candida control, but also are ideal for the prevention of other chronic disease states such as cancer, high blood pressure, heart disease, and diabetes.4

Diabetics Should Follow These Simple Recommendations

  1. Consume a diet that is high in "good" fats such as butter, coconut oil, lard and other natural occuring animal fats as discussed in Fats & Oils from The Skinny on Fats By Mary Enig, PhD, and Sally Fallon.
    A high fats diet is also recommended by Dr. Jan Kwasniewski, in Poland, who has been curing people of diabetes and other serious illnesses with his Optimal Diet for over 30 years.
  2. Go on a low-carb diet. Carbs are defined as all foods that are not classified as protein or fat. That includes eliminating all sugars (including fruits), grains, nuts, starches and high-carb foods, i.e. cereal, bread, pastries, donuts, cakes, cookies, pasta, carrots, potatoes, beets, etc. - see this food list, which is for candida sufferers, but this diet is also very important for diabetics.
    Did you know that you can be perfectly healthy not eating carbs of any kind? That is because 58% of protein and 10% of "good" fats turns into glucose inside the body providing all the body requires for maintaining blood sugar levels.
  3. Eat a moderate protein diet.
  4. Eliminate as many sources of toxins as possible, including drugs, processed foods, and toxins in the environment, personal care products, cleaning products, etc. See Toxins, Vegetable Oils' Toxic Effects, Food Facts & Information [includes toxic & damaging foods]and Sugar, Fruit, Sugar Substitutes & Artificial Sweeteners.
  5. Take Supplements that together with the diet will provide all of the nutrients your body requires. The body can heal itself when it is given the proper nutrients to do its job!
  6. Eat Enough Food! Inadequate food intake over an extended time will cause many problems – including fatigue, weakness, depression, irritability, sleep disturbance, headaches, muscle aches and pains, numbness and tingling, frequent urination and water retention. Many of these symptoms also resemble Type II diabetes. Not eating enough food can in fact lead to medical problems such as high blood pressure, diabetes, and weight problems, including obesity.3
  7. Eating small meals may make the problem worse. Consistently eating less than you need to make you feel full can stimulate your body's natural starvation defenses – and you feel hungry, crave sweets, and become tire, irritable, depressed, etc. In addition, eating small meals can inhibit insulin production, causing more blood sugar problems. Nutritional deficiencies are more common when eating small meals, which can aggravate the conditions that cause blood sugar problems.5
  8. Eat until you feel full at least twice a day. You can eat more often, but at least two times a day you should eat until you feel full.5

References

Saturday 27 July 2013

MS and Fabry Disease or is it Candida?????

 If at first misdiagnosed with MS a condition that I believe doesn't exist, so my conclusions are that Candida is the  problem, which will not show up in a blood test

 ////////////////////////////////////////////////////////////////////////

Prevalence of Fabry Disease in a Defined Population at Risk - Patients Formerly Diagnosed With Multiple Sclerosis

This study is currently recruiting participants.
Verified March 2013 by University of Rostock
Sponsor:
Information provided by (Responsible Party):
Prof. Dr. Arndt Rolfs, University of Rostock
ClinicalTrials.gov Identifier:
NCT01271699
First received: January 6, 2011
Last updated: March 15, 2013
Last verified: March 2013
  Purpose
The association of Multiple Sclerosis (MS) and Fabry disease is known from own clinical experiences as well as from case reports in the literature, where symptoms and suspicious results in the brain MRI led to the misdiagnosis of Fabry patients as MS. Remarkably, those patients almost never showed oligoclonal bands or an intrathecally derived IgG-production was wrongly assumed due to misinterpretation of CSF results. Where oligoclonal bands were present, concomitant diagnoses had to be discussed. Furthermore, those patients showed no involvement of the spinal cord, as evidenced by MRI. Beside the possible complications of a not-effective and not-necessary MS therapy, those patients are at risk of irreparable organ damage due to the delayed implementation of enzyme replacement therapy for Fabry disease.

Condition
Multiple Sclerosis

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Retrospective
Official Title: Multiple Sclerosis and Fabry Disease: Prevalence of Fabry Disease in a Defined Population at Risk - Patients Formerly Diagnosed With Multiple Sclerosis - an Epidemiological Study

Resource links provided by NLM:


Further study details as provided by University of Rostock:

Biospecimen Retention:   Samples With DNA
Fabry diagnostic will be done centrally: blood samples will be stored for analysis of a-galactosidase in blood, Gb3 as well as lyso-Gb3. In all cases direct analysis of the gene will be done, especially in females where due to the Lyonisation effect a-galactosidase activity might be normal in blood although the patient might suffer from Fabry disease.

Estimated Enrollment: 250
Study Start Date: January 2011
Estimated Study Completion Date: March 2015
Estimated Primary Completion Date: February 2015 (Final data collection date for primary outcome measure)
Groups/Cohorts
Observation
Patients at age 18-50 with a confirmed or probably diagnosis of Multiple Sclerosis according to the McDonald diagnostic criteria for MS

Detailed Description:
Fabry disease is an X-linked lysosomal disorder that leads to excessive deposition of neutral glycosphingolipids in the vascular endothelium of several organs in the body. Progressive endothelial accumulation of glycosphingolipids accounts for the associated clinical abnormalities of skin, eye, kidney, heart, brain, and peripheral nervous system. Fabry disease manifesting predominantly in men. Female heterozygotes also present with features of Fabry disease. In Europe the prevalence of Fabry disease seems to be massively underrepresented.
Multiple Sclerosis (MS, Encephalomyelitis disseminata) ist the most common inflammatory disease of the central nervous system (CNS). The first clinical manifestation peaks in the 3rd-4th decade. 2.5 million Young adults are affected worldwide. In Germany the prevalence rate reaches approx. 100 patients per 100,000 inhabitants. Females are more frequently affected (2-3:1). The underlying causes of the disease are not sufficiently explored yet. The genetic backgrounds as well as environmental factors are involved. An autoimmune mediated process, driven by activated T-lymphocytes and macrophages, leads to inflammatory demyelination and axonal loss.
Magnetresonance imaging of the brain and spinal cord, evaluation of the cerebrospinal fluid to detect intrathecally derived immunoglobulin production (IgG) and a comprehensive diagnostic workup on other possible causes of the symptoms. The modern diagnostic criteria (McDonald criteria, 2001 + revisions 2005) demand the proof of the dissemination of the inflammatory process in space and time, either by clinical or radiological terms.
The evaluation of the cerebrospinal fluid aims at the confirmation of an intrathecally derived synthesis of IgG. In 98% of the patients oligoclonal bands can be detected during the course of the disease. This parameter is highly sensitive but only low specific. The diagnostic criteria allow making the diagnosis of "certain" or at least "probable" MS without the confirmation of oligoclonal bands.
  EligibilityF

is Candida linked to Fabry disease??????????????

Fabry Disease:

Fabry disease results from abnormal deposits of a particular fatty substance (called globotriaosylcera-mide) in blood vessel walls throughout the body. The primary defect which allows this to occur is the inherited deficiency of the enzyme, alpha galactosidase A, which is normally responsible for the breakdown of globotriaosylceramide.

Metabolic Defect
The body continuously performs metabolic processes which produce, recycle and remove vital compounds. In patients with Fabry disease one such common compound formed of three sugars and a fatty substance (globotriaosylceramide) does not get broken down due to the missing or non-functioning enzyme alpha galactosidase A. Since this fatty compound (lipid) is not being broken down and removed, it begins to accumulate. Thus, Fabry disease is often referred to as a "storage disorder" due to this abnormal accumulation. In patients with Fabry disease, this accumulation occurs primarily in the blood and in the walls of blood vessels. As the abnormal storage of this fatty compound increases with time, the channels of these vessels become narrowed, leading to decreased blood flow and decreased nourishment of the tissues normally supplied by these vessels. This abnormal process occurs in blood vessels throughout the body, particularly affecting vessels in the skin, kidneys, heart, brain and nervous system.

Disease Inheritance
Fabry disease is an inherited disorder. The defective gene is on the X-chromosome, which is one of the two chromosomes that determine an individual’s sex. Females have two X chromosomes, one inherited from each of their parents. Males have one X chromosome inherited from their mother and one Y chromosome inherited from their father. A female with Fabry receive one X chromosome with a defective gene and one X chromosome with the normal gene, and thus often has some protection from the major manifestations of the disease. This is not always the case though as there is a high degree of variability in females. Males with Fabry disease receive only one abnormal X chromosome that contains the abnormal gene and thus express the disease.

All male and female children of an affected female have a 50% chance of inheriting the defective gene from their mother. If the father is the one carrying the Fabry gene all female children will inherit the defective gene and all male children will not. The inheritance pattern of Fabry disease is called X-linked inheritance. Fabry disease occurs in all ethnic groups. It is estimated that one person in 40,000 has Fabry disease.

Clinical Symptoms

    Males
    Typically, the disease begins in childhood with episodes of pain and burning sensations in the hands and feet. In addition, young patients often develop a spotted, dark red skin rash (angiokeratomas) seen most densely from the umbilicus to the knees, a decreased ability to perspire, and a characteristic change on the cornea of the eye which does not affect vision. The painful episodes may be brought on by exercise, fever, fatigue, stress, or change in weather conditions. The disease is slowly progressive and symptoms of kidney, heart and/or neurologic involvement usually occur between the ages of 30 to 45. Many patients are first diagnosed when the accumulated storage material begins to affect kidney or heart function. Therefore, it is important to annually monitor kidney function by blood and urine tests because kidney disease is a major complication that can occur in affected males.
    A common heart symptom in Fabry patients is mitral valve prolapse, which is a benign condition that is present in approximately 10% of the normal population. More serious, but rarer, complications of Fabry disease include heart disease and strokes.
    Other symptoms may include varying degrees of abdominal discomfort, frequent bowel movements shortly after eating, joint pain, back pain primarily in the kidney region or ringing of the ears (tinnitus).

    Females
    Females may show a wide range of clinical manifestations. Some individuals remain completely asymptomatic and have normal levels of a gal a while some are as severely affected as hemizygous males. This variability is most likely to be caused by random inactivation of one copy of the X-chromosome in each cell. The most common symptom of Fabry disease seen in heterozygous females is corneal dystrophy, which occurs in around 70% of females. Other symptoms that have been reported in females with Fabry disease include: angiokeratomas, acroparesthesias, anhidrosis, gastrointestinal disturbances, vascular lesions in the conjunctiva and retina, kidney disease, autonomic and other neurological complications such as tinnitus and vertigo, cardiovascular abnormalities, cerebrovascular abnormalities, fatigue. Women may often be misdiagnosed as having lupus or other conditions.

    Children
    Although the signs and symptoms of Fabry disease generally appear during childhood, the diagnosis may often be missed. The earliest symptoms of Fabry disease in children are usually pain and angiokeratomas. The pain may, however, be dismissed as 'growing pains', while angiokeratomas may be overlooked during a routine clinical examination, particularly if they are confined to locations such as the backs of the ears. Cardiac and renal involvement can also begin in childhood, thus early diagnosis and careful monitoring are necessary. Other symptoms include Hypohidrosis (inability to sweat), GI symptoms that mimic chronic inflammatory bowel disease, recurrent nausea and vomiting, vertigo, tinnitus, headaches, fevers.
Treatment
Pain associated with Fabry disease can be difficult to treat but usually responds to medications such as Tegretol (carbamazepine), Dilantin or Neurotin. Metoclopramide, Lipisorb (a nutritional supplement), Pancrelipase may be beneficial in treating Gastrointestinal hyperactivity. Early experiments with enzyme replacement therapy indicate promising results.

Thursday 25 July 2013

Atlas and Lhermittes indicative of ms

Candida and OCD


Candida symptoms

Here is a list of symptoms and conditions that commonly occur in people with Candida overgrowth.  Most all of these same symptoms typically improve or disappear with effective treatment for Candida.
Some of the symptoms listed may sound “normal,” because the Candida problem is so common in the modern world.  Some are led to say, when they review this list, “Doesn’t that describe everybody?”  It must be emphasized that none of these symptoms are part of normal health.  When too many people around us are ill, strange symptoms may become common, but that does not make them normal.  Many of the things listed — such as asthma, diabetes, epidemic obesity, chronic fatigue, fibromyalgia, ADD/ADHD, autism, panic attacks and others — were virtually non-existent (or at least much less common) before the 1970s.  They became much too common as a consequence of various factors, including:  widespread overuse of antibiotics starting in the 1950s; increased availability of chlorinated swimming pools; much increased use of pesticides, hormones and antibiotics in the food supply; the advent of the birth control pill; and the addition since the 1990s of barley malt into nearly every baked food (cereals, crackers, cookies) and of high-fructose corn syrup as a sweetener in beverages.
A person with Candida overgrowth may have only 2-3 of these symptoms, or may identify with many.
Mental/emotional/nervous system:
  • Headaches and migraine headaches
  • Depression
  • Sleep problems — difficulty falling asleep, or waking up in the middle of the night with a mind that won’t calm down (typically between 1 and 3 am)
  • Irritability and confusion
  • Poor memory
  • Anxiety attacks, panic attacks
  • Obsessive-compulsive disorder (OCD)
  • Heart beating too fast or irregularly
  • Sexual problems — impotence or lack of desire, or excessive sexuality
  • Attention deficit, hyperactivity (ADD/ADHD)
  • Dizziness
  • Numbness
  • Feeling of floating or not quite being in your body
  • Indecisiveness, difficulty organizing and cleaning messy areas
Digestive system:
  • Cravings for sugar, chocolate, milk, cheese, vinegar, pickles, alcohol, bread, nuts or fruit
  • “Metabolic syndrome” which includes the following: large abdomen (“beer belly”), adult-onset diabetes, high cholesterol or triglycerides, high blood pressure
  • “Beer belly,” also called truncal obesity — excess weight centered around the abdomen
  • Acid reflux/GERD (heartburn)
  • Hypoglycemia (low blood sugar)
  • Bloating, flatulence or abdominal pain
  • Rectal itching
  • Constipation and/or diarrhea
  • Excessively thin or anorexic/bulimic
Skin, eyes, hair:
  • Skin and nail fungal infections (current or past), including: athlete's foot, vaginal yeast infections, fungal toenails, ringworm, jock itch, tinea versicolor or itchy eyelids
  • Skin problems like eczema, rashes, psoriasis
  • Prematurely graying hair
  • Pupils always dilated
  • Unusually green eyes, or eye color has turned greenish
Immune disorders:
  • Asthma and allergies
  • Recurring infections — colds, ears, bladder, sinus
  • Autoimmune disease (lupus, hypothyroidism, arthritis, others)
  • Penicillin allergy
Whole body:
  • Fatigue
  • Muscle or joint pain, fibromyalgia
  • Cold feet, cold hands, sometimes cold nose
  • Sweating, especially at night
  • Uncomfortable at any temperature
Women’s health issues:
  • Premenstrual syndrome (PMS)
  • Endometriosis (chronic pelvic pain)
  • Infertility (female), some miscarriages, toxemia of pregnancy (preeclampsia)
Symptoms seen particularly in children up to about 8 years old:
  • Early allergy to foods like milk
  • Infections as a baby
  • Child had or has frequent ear infections, tonsillitis, strep throat or bladder infections, especially if these infections were treated with antibiotics
  • Cravings for milk, cheese, yogurt, macaroni and cheese, or peanut butter
  • Asthma
  • “Drama king” or “drama queen” — complains quite vocally and often
  • Poor sleep patterns — difficulty going to sleep, sleeps too lightly or has frequent nightmares, and wakes up too early (or sometimes too late)
  • Too thin or overweight
  • Attention deficit with or without hyperactivity (ADD/ADHD)
  • Aggressive, poor social interactions, can’t stop moving, frequent fights or arguments, frequent crying
  • Autism
  • Pale complexion, dark circles under the eyes
Two points should be understood with regard to the above list of signs and symptoms of Candida overgrowth.  First, while all of the symptoms listed are definitely seen in Candida patients and evidence indicates Candida causes or strongly contributes to the development of these problems, there are other contributing factors that can also bring about some of these problems (such as mercury or other metal toxicity, consistent excess electromagnetic field exposure, underlying viral infections, petrochemical exposure, etc.).  Second, treatment for Candida alone will usually bring about significant improvement in these symptoms, but will not be adequate in all cases to restore health.  Often additional treatments aimed at improving liver, adrenal or thyroid function, or correcting immune and allergic problems, are necessary to regain health.

is BPPV Atlas related????????

Symptoms

By Mayo Clinic staff The signs and symptoms of benign paroxysmal positional vertigo (BPPV) may include:
  • Dizziness
  • A sense that you or your surroundings are spinning or moving (vertigo)
  • Lightheadedness
  • Unsteadiness
  • A loss of balance
  • Blurred vision associated with the sensation of vertigo
  • Nausea
  • Vomiting
The signs and symptoms of BPPV can come and go, with symptoms commonly lasting less than one minute. Episodes of benign paroxysmal positional vertigo and other forms of vertigo can disappear for some time and then recur.
Activities that bring about the signs and symptoms of BPPV can vary from person to person, but are almost always brought on by a change in the position of your head. Abnormal rhythmic eye movements (nystagmus) usually accompany the symptoms of benign paroxysmal positional vertigo. Although rare, it's possible to have BPPV in both ears (bilateral BPPV).
When to see a doctor
Generally, see your doctor if you experience any unexplained dizziness or vertigo that recurs periodically for more than one week.
Seek emergency care
Although it's uncommon for dizziness to signal a serious illness, see your doctor immediately if you experience dizziness or vertigo along with any of the following:
  • A new, different or severe headache
  • A fever of 101 F (38 C) or higher
  • Double vision or loss of vision
  • Hearing loss
  • Trouble speaking
  • Leg or arm weakness
  • Loss of consciousness
  • Falling or difficulty walking
  • Numbness or tingling
  • Chest pain, or rapid or slow heart rate
The signs and symptoms listed above may signal a more serious problem, such as stroke or a cardiac condition.