Caffeine addiction
From Wikipedia, the free encyclopedia
Caffeinism | |
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Classification and external resources | |
ICD-10 | F15 |
Caffeine's mechanism of action is somewhat different from that of many other addictive drugs, such as cocaine or the amphetamines. Caffeine antagonizes, or blocks, adenosine receptors. Adenosine is a by-product of cellular activity, and the adenosine receptors play a role in producing feelings of tiredness and the need to sleep. Caffeine's ability to block these receptors means the levels of the body's natural stimulants, dopamine and norepinephrine continue at higher levels. While the drug is active, adenosine site antagonization increases, as do levels of neurotransmitters.
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