>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>
Stiff-Person Syndrome Definition
Stiff-Person syndrome: a rare neurological disorder with features of an autoimmune disease, characterized by fluctuating muscle rigidity in the trunk and limbs and an enhanced sensitivity to stimuli such as noise, touch, and emotional distress. Muscle spasms may also be present as a result of the sensitivity to various stimuli, leading to abnormal postures and stiffening. Stiff-Person syndrome (SPS) is more common in women than in men and is often associated with other autoimmune diseases including, pernicious anemia, diabetes, vitiligo, and thyroiditis. The exact cause of Stiff-Person syndrome is unknown, but it appears to result from an autoimmune reaction.SOURCE:
MedTerms.com. Stiff-Person syndrome.
What is Stiff-Person syndrome?
What are the signs and symptoms of Stiff-Person syndrome?
Comment on this
Stiff-Person syndrome is characterized by fluctuating muscle rigidity in
the trunk and limbs and a heightened sensitivity to stimuli such as noise,
touch, and emotional distress, which can set off muscle spasms. Abnormal
postures, often hunched over and stiffened, are characteristic of the disorder.
People with Stiff-Person syndrome can be too disabled to walk or move, or they are afraid to leave
the house because street noises, such as the sound of a horn, can trigger spasms
and falls. Who is affected by, and what causes Stiff-Person syndrome?
How is Stiff-Person syndrome diagnosed?
Comment on this
The disorder is often misdiagnosed as Parkinson's disease,
multiple sclerosis, fibromyalgia, psychosomatic illness, or anxiety and phobia.
A definitive diagnosis can be made with a blood test that measures the level of
glutamic acid decarboxylase (GAD) antibodies in the blood. People with
Stiff-Person syndrome have
elevated levels of GAD, an antibody that works against an enzyme involved in the
synthesis of an important neurotransmitter in the brain.
No comments:
Post a Comment